Natural alginate biopolymer montmorillonite clay composites for vitamin B2 delivery

Hakan Kaygusuz, Mutlu Uysal, Veselina Adimcilar, F. Bedia Erim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)


This work describes the in vitro release of a small drug, riboflavin, from novel calcium and barium crosslinked alginate-montmorillonite composite beads via oral route. Effect of crosslinking cation, concentration of montmorillonite and media on encapsulation efficiencies, and release profiles of riboflavin were studied. Beads were characterized using gravimetric swelling ability study, Fourier transform infrared spectroscopy, and scanning electron microscopy. Results indicate that addition of montmorillonite increases the encapsulation efficiencies and slows down the release rates significantly.

Original languageEnglish
Pages (from-to)48-56
Number of pages9
JournalJournal of Bioactive and Compatible Polymers
Issue number1
Publication statusPublished - 17 Jan 2015

Bibliographical note

Publisher Copyright:
© The Author(s) 2015.


  • alginate
  • biopolymer
  • montmorillonite
  • release
  • Riboflavin


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