Monitoring of neomycin sulfate antibiotic in microbial fuel cells

Tunc Catal*, Sehnaz Yavaser, Vildan Enisoglu-Atalay, Hakan Bermek, Selma Ozilhan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)


Indirect detection and quantification of the neomycin sulfate antibiotic was accomplished in microbial fuel cells. Performance of the microbial fuel cells was examined on the basis of the following parameters; voltage generation, power density, current density and coulombic efficiencies. Removal of neomycin sulfate was monitored using LC-MS/MS in parallel with chemical oxygen demand and total carbohydrate removal. While neomycin sulfate was partially degraded, microbial fuel cell performance appeared to be affected and eventually inhibited by neomycin sulfate on a concentration-based fashion. In order to further examine the neomycin sulfate bio-sensing activity of the microbial fuel cell, a computational chemistry approach was used to obtain the information about the highest occupied molecular orbital-lowest unoccupied molecular orbital energy values of outer electron orbitals, their distribution, and ionization potentials (IPs). The results showed that electroactive bio-film-based MFCs can be used for sensitive detection of neomycin sulfate found in wastewaters.

Original languageEnglish
Pages (from-to)116-120
Number of pages5
JournalBioresource Technology
Publication statusPublished - Nov 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Ltd


  • Antibiotic
  • Biosensor
  • Electricity
  • Microbial fuel cell
  • Neomycin sulfate
  • Wastewater


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