TY - JOUR
T1 - Monitoring of Hypochlorite Level in Fruits, Vegetables, and Dairy Products
T2 - A BODIPY-Based Fluorescent Probe for the Rapid and Highly Selective Detection of Hypochlorite
AU - Suna, Garen
AU - Erdemir, Eda
AU - Gunduz, Simay
AU - Ozturk, Turan
AU - Karakuş, Erman
N1 - Publisher Copyright:
© 2023 The Authors. Published by American Chemical Society
PY - 2023/6/27
Y1 - 2023/6/27
N2 - Hypochlorite/hypochlorous acid (ClO-/HOCl), among the diverse reactive oxygen species, plays a vital role in various biological processes. Besides, ClO- is widely known as a sanitizer for fruits, vegetables, and fresh-cut produce, killing bacteria and pathogens. However, excessive level of ClO- can lead to the oxidation of biomolecules such as DNA, RNA, and proteins, threatening vital organs. Therefore, reliable and effective methods are of utmost importance to monitor trace amounts of ClO-. In this work, a novel BODIPY-based fluorescent probe bearing thiophene and a malononitrile moiety (BOD-CN) was designed and constructed to efficiently detect ClO-, which exhibited distinct features such as excellent selectivity, sensitivity (LOD = 83.3 nM), and rapid response (<30 s). Importantly, the probe successfully detected ClO- in various spiked water, milk, vegetable, and fruit samples. In all, BOD-CN offers a clearly promising approach to describe the quality of ClO--added dairy products, water, fresh vegetables, and fruits.
AB - Hypochlorite/hypochlorous acid (ClO-/HOCl), among the diverse reactive oxygen species, plays a vital role in various biological processes. Besides, ClO- is widely known as a sanitizer for fruits, vegetables, and fresh-cut produce, killing bacteria and pathogens. However, excessive level of ClO- can lead to the oxidation of biomolecules such as DNA, RNA, and proteins, threatening vital organs. Therefore, reliable and effective methods are of utmost importance to monitor trace amounts of ClO-. In this work, a novel BODIPY-based fluorescent probe bearing thiophene and a malononitrile moiety (BOD-CN) was designed and constructed to efficiently detect ClO-, which exhibited distinct features such as excellent selectivity, sensitivity (LOD = 83.3 nM), and rapid response (<30 s). Importantly, the probe successfully detected ClO- in various spiked water, milk, vegetable, and fruit samples. In all, BOD-CN offers a clearly promising approach to describe the quality of ClO--added dairy products, water, fresh vegetables, and fruits.
UR - http://www.scopus.com/inward/record.url?scp=85163466845&partnerID=8YFLogxK
U2 - 10.1021/acsomega.3c02069
DO - 10.1021/acsomega.3c02069
M3 - Article
AN - SCOPUS:85163466845
SN - 2470-1343
VL - 8
SP - 22984
EP - 22991
JO - ACS Omega
JF - ACS Omega
IS - 25
ER -