Microwave Dielectric properties of Osteosarcoma Cell Line (SAOS-2) Suspensions

Zeynep Macit, Cemanur Aydinalp, Tuba Yilmaz, Ayse Buse Ozdabak Sert, Fatma Nese Kok

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)

Abstract

Dielectric properties of biological tissues have been limited to some in vivo animal and mostly ex vivo animal and human tissue measurements. Recent studies showed that factors changing after the excision of tissue such as temperature, heterogeneity, hydration can significantly alter the dielectric properties. However, due to the challenging nature of performing dielectric properties on living tissues, the underlying factors of dielectric property discrepancy between diseased and healthy tissues remains an open question. As building blocks of tissues, cells can serve as an alternative sample to living tissue to explore the fundamental dielectric property discrepancy between normal and diseased tissues. With this motivation, we are reporting two different concentrations of Osteosarcoma Cell Line (SAOS-2) suspended in Dulbecco's Modified Eagle Medium (DMEM) dielectric property measurements. Dielectric property measurements are performed with the open-ended coaxial probe technique between 500 MHz to 18 GHz. A very small decrease (0.5 units) is observed between the relative permittivity of pure DMEM and cell suspension. Similarly, the difference between dielectric properties of 12,500,000 SAOS-2 cell suspensions and 22,500,000 SAOS-2 cell suspensions is found to be small and inconsistent at frequencies between 500 MHz to 18 GHz.

Original languageEnglish
Title of host publicationICECOM 2019 - 23rd International Conference on Applied Electromagnetics and Communications, Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781728155142
DOIs
Publication statusPublished - Sept 2019
Event23rd International Conference on Applied Electromagnetics and Communications, ICECOM 2019 - Dubrovnik, Croatia
Duration: 30 Sept 20192 Oct 2019

Publication series

NameICECOM 2019 - 23rd International Conference on Applied Electromagnetics and Communications, Proceedings

Conference

Conference23rd International Conference on Applied Electromagnetics and Communications, ICECOM 2019
Country/TerritoryCroatia
CityDubrovnik
Period30/09/192/10/19

Bibliographical note

Publisher Copyright:
© 2019 IEEE.

Funding

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 750346, Cost Action CA17115, and from the Istanbul Technical University grant 41554.

FundersFunder number
Marie Sklodowska-Curie750346, CA17115
Horizon 2020 Framework Programme
Istanbul Teknik Üniversitesi41554

    Keywords

    • SAOS-2
    • cell suspension
    • dielectric properties
    • open-ended coaxial probes

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