Mesenchymal stem cell differentiation by nano-engineered Si columns

Levent Trabzon*, Mustafa Ramazanoglu, Huseyin Kizil, Sebahattin Guvendik

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We successfully engineered Si nano-columns with different cross-sectional geometries by e-beam evaporation with an angle between source and substrate. The Si nano-columns were grown as pillars with square, triangle and linear cross sections in in-plane. Mesenchymal stem cells (MSCs) isolated from the bone marrow stroma of young adult rats were cultured on these different Si nanosurfaces. We found that the behaviour of MSCs highly depended on the geometry of nano-topography so that mesenchymal stem cells were differentiated and induced CaP precipitation on square-cross-sectional Si nano-columns without growth factor in the culture medium.

Original languageEnglish
Title of host publication2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011
Pages45-48
Number of pages4
DOIs
Publication statusPublished - 2011
Event2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011 - Sharjah, United Arab Emirates
Duration: 21 Feb 201124 Feb 2011

Publication series

Name2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011

Conference

Conference2011 1st Middle East Conference on Biomedical Engineering, MECBME 2011
Country/TerritoryUnited Arab Emirates
CitySharjah
Period21/02/1124/02/11

Keywords

  • Biomaterials
  • Nano-Columns
  • Stem Cells

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