Mercury-free mouse ICSI with rotationally oscillating drill (Ros-Drill©)

Ali Fuat Ergenc, Ming Wen Li, Mehmet Toner, John D. Biggers, K. C.Kent Lloyd, Nejat Olgac

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

ICSI (intracytoplasmic sperm injection) is an important and commonly used assisted reproductive technology (ART) in humans and animals. However, conventional ICSI has proven to be difficult and inefficient, especially in mice. Fortunately, the application of piezo-electric technology to assist the injection process has made ICSI more effective and efficient in recent years. Despite this advance, the pipette tip is unstable in response to the force exerted by the piezoelectric pulse during injection. To some extent, this instability can be mitigated by the use of mercury, which is highly toxic. In an effort to overcome these hurdles, we developed and tested a completely different and mercury-free technology, called the "Ros-Drill

Original languageEnglish
Title of host publicationNEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781424443628
DOIs
Publication statusPublished - 2009
EventIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009 - Boston, MA, United States
Duration: 3 Apr 20095 Apr 2009

Publication series

NameProceedings of the IEEE Annual Northeast Bioengineering Conference, NEBEC
ISSN (Print)1071-121X

Conference

ConferenceIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009
Country/TerritoryUnited States
CityBoston, MA
Period3/04/095/04/09

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