Abstract
The regularization of retinal oxygen tension estimation was previously proposed with an assumption that phosphorescence intensity images are corrupted by additive Gaussian noise. Based on this assumption, a regularized least-squares estimate has been shown to be better than a conventional least-squares estimation. However, this assumption is inconsistent with the acquisition process of phosphorescence intensity images acquired using an intensified charge-coupled device camera. Almost the entire acquisition process is governed by the natural aspects of photons. Therefore, a method based on photon counting statistics is more appropriate. In this study, we propose a regularized oxygen tension estimation method based on photon counting statistics and a phosphorescence lifetime imaging model.
| Original language | English |
|---|---|
| Pages (from-to) | 2163-2169 |
| Number of pages | 7 |
| Journal | IEEE Transactions on Biomedical Engineering |
| Volume | 71 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1 Jul 2024 |
Bibliographical note
Publisher Copyright:© 1964-2012 IEEE.
Keywords
- Intensified charge-coupled device camera
- maximum-a-posterior estimation
- oxygen tension estimation
- photon counting statistics
- poisson noise