Maslinic acid as an effective anticancer agent

Xiukun Lin; Ulku Ozbey; Yerzhan Sabitaliyevich Uteuliyev; Rukset Attar; Beraat Ozcelik; Yuanyan Zhang; Mingyue Guo; Minghua Liu; Saleh S. Alhewairini; Ammad Ahmad Farooqi

doi:10.14715/cmb/2018.64.10.14

Maslinic acid as an effective anticancer agent

Xiukun Lin
, Ulku Ozbey
, Yerzhan Sabitaliyevich Uteuliyev
, Rukset Attar
, Beraat Ozcelik
, Yuanyan Zhang
, Mingyue Guo
, Minghua Liu
, Saleh S. Alhewairini
, Ammad Ahmad Farooqi^*

^*Corresponding author for this work

Department of Food Engineering

Southwest Medical University
Munzur Universitesi
Kazakhstan Medical University
Yeditepe University
Qassim University
Institute of Biomedical and genetic Engineering (IBGE)

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.

Original language	English
Pages (from-to)	87-91
Number of pages	5
Journal	Cellular and Molecular Biology
Volume	64
Issue number	10
DOIs	https://doi.org/10.14715/cmb/2018.64.10.14
Publication status	Published - 2018

Bibliographical note

Publisher Copyright:
© 2018 by the C.M.B. Association.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Apoptosis
Cancer
Maslinic acid
Signaling

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10.14715/cmb/2018.64.10.14

Cite this

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title = "Maslinic acid as an effective anticancer agent",

abstract = "Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.",

keywords = "Apoptosis, Cancer, Maslinic acid, Signaling",

author = "Xiukun Lin and Ulku Ozbey and Uteuliyev, \{Yerzhan Sabitaliyevich\} and Rukset Attar and Beraat Ozcelik and Yuanyan Zhang and Mingyue Guo and Minghua Liu and Alhewairini, \{Saleh S.\} and Farooqi, \{Ammad Ahmad\}",

note = "Publisher Copyright: {\textcopyright} 2018 by the C.M.B. Association.",

year = "2018",

doi = "10.14715/cmb/2018.64.10.14",

language = "English",

volume = "64",

pages = "87--91",

journal = "Cellular and Molecular Biology",

issn = "0145-5680",

publisher = "Cellular and Molecular Biology Association",

number = "10",

}

TY - JOUR

T1 - Maslinic acid as an effective anticancer agent

AU - Lin, Xiukun

AU - Ozbey, Ulku

AU - Uteuliyev, Yerzhan Sabitaliyevich

AU - Attar, Rukset

AU - Ozcelik, Beraat

AU - Zhang, Yuanyan

AU - Guo, Mingyue

AU - Liu, Minghua

AU - Alhewairini, Saleh S.

AU - Farooqi, Ammad Ahmad

PY - 2018

Y1 - 2018

N2 - Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.

AB - Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.

KW - Apoptosis

KW - Cancer

KW - Maslinic acid

KW - Signaling

UR - https://www.scopus.com/pages/publications/85051815468

U2 - 10.14715/cmb/2018.64.10.14

DO - 10.14715/cmb/2018.64.10.14

M3 - Article

C2 - 30084808

AN - SCOPUS:85051815468

SN - 0145-5680

VL - 64

SP - 87

EP - 91

JO - Cellular and Molecular Biology

JF - Cellular and Molecular Biology

IS - 10

ER -

Maslinic acid as an effective anticancer agent

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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