Lip balm drying promotes virus attachment: Characterization of lip balm coatings and XDLVO modeling

Xunhao Wang; Reyhan Şengür-Taşdemir; İsmail Koyuncu; Volodymyr V. Tarabara

doi:10.1016/j.jcis.2020.07.143

Lip balm drying promotes virus attachment: Characterization of lip balm coatings and XDLVO modeling

Xunhao Wang, Reyhan Şengür-Taşdemir, İsmail Koyuncu, Volodymyr V. Tarabara^*

^*Corresponding author for this work

Department of Environmental Engineering

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Hypothesis: Drying-induced decrease in lip balm surface energy enhances virus adhesion due to the emergence of strong hydrophobic colloid-surface interactions. Experiments: A protocol was developed for preparing lip balm coatings to enable physicochemical characterization and adhesion studies. Surface charge and hydrophobicity of four brands of lip balm (dry and hydrated) and human adenovirus 5 (HAdV5) were measured and used to calculate the extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) energy of interactions between lip balm coatings and HAdV5 as well as four other colloids: HAdV40, MS2 and P22 bacteriophages, and SiO₂. Quartz crystal microbalance with dissipation monitoring (QCM-D) tests employed SiO₂ colloids, HAdV5 and hydrated lip balms. Findings: Drying of lip balms results in a dramatic decrease of their surface energy (δΔG_sws≥ 83.0 mJ/m²) making the surfaces highly hydrophobic. For dry lip balms, the interaction of the balm surface with all five colloids is attractive. For lip balms hydrated in 150 mM NaCl (ionic strength of human saliva), XDLVO calculations predict that hydrophilic colloids (MS2, P22, SiO₂) may attach into shallow secondary minima. Due to the relative hydrophobicity of human adenoviruses, primary maxima in XDLVO profiles are low or non-existent making irreversible deposition into primary energy minima possible. Preliminary QCM-D tests with SiO₂ colloids and HAdV5 confirm deposition on hydrated lip balms.

Original language	English
Pages (from-to)	884-894
Number of pages	11
Journal	Journal of Colloid and Interface Science
Volume	581
DOIs	https://doi.org/10.1016/j.jcis.2020.07.143
Publication status	Published - 1 Jan 2021

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Inc.

Funding

This material is based upon work supported in part by the National Science Foundation Partnerships for International Research and Education program under Grant IIA-1243433 and in part by the Center for European, Russian and Eurasian Studies at Michigan State University (MSU). We thank Dr. Hang Shi (CTI and Associates, Inc.), Dr. Irene Xagoraraki (Civil and Environmental Engineering, MSU) and Dr. Kristin Parent (Biochemistry and Molecular Biology, MSU) for useful discussions as well as to Dr. Wei Zhang (Department of Plant, Soil and Microbial Sciences, MSU) for providing access to Malvern Zetasizer Nano ZS. We are also thankful to Mrs. Carol Flegler (Center for Advanced Microscopy, MSU) for recording SEM images and advising on appropriate sample preparation procedures. This material is based upon work supported in part by the National Science Foundation Partnerships for International Research and Education program under Grant IIA-1243433 and in part by the Center for European, Russian and Eurasian Studies at Michigan State University (MSU). We thank Dr. Hang Shi (CTI and Associates, Inc.), Dr. Irene Xagoraraki (Civil and Environmental Engineering, MSU) and Dr. Kristin Parent (Biochemistry and Molecular Biology, MSU) for useful discussions as well as to Dr. Wei Zhang (Department of Plant, Soil and Microbial Sciences, MSU) for providing access to Malvern Zetasizer Nano ZS. We are also thankful to Mrs. Carol Flegler (Center for Advanced Microscopy, MSU) for recording SEM images and advising on appropriate sample preparation procedures.

Funders	Funder number
Associates, Inc.
Center for European, Russian and Eurasian Studies at Michigan State University
Civil and Environmental Engineering
Department of Plant, Soil and Microbial Sciences
National Science Foundation	IIA-1243433
Midwestern State University

Keywords

Adenovirus
Adhesion
Fomites
Lip balm
Lipstick
Personal care products
Public health
QCM-D
Virus transfer
XDLVO

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10.1016/j.jcis.2020.07.143

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title = "Lip balm drying promotes virus attachment: Characterization of lip balm coatings and XDLVO modeling",

abstract = "Hypothesis: Drying-induced decrease in lip balm surface energy enhances virus adhesion due to the emergence of strong hydrophobic colloid-surface interactions. Experiments: A protocol was developed for preparing lip balm coatings to enable physicochemical characterization and adhesion studies. Surface charge and hydrophobicity of four brands of lip balm (dry and hydrated) and human adenovirus 5 (HAdV5) were measured and used to calculate the extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) energy of interactions between lip balm coatings and HAdV5 as well as four other colloids: HAdV40, MS2 and P22 bacteriophages, and SiO2. Quartz crystal microbalance with dissipation monitoring (QCM-D) tests employed SiO2 colloids, HAdV5 and hydrated lip balms. Findings: Drying of lip balms results in a dramatic decrease of their surface energy (δΔGsws≥ 83.0 mJ/m2) making the surfaces highly hydrophobic. For dry lip balms, the interaction of the balm surface with all five colloids is attractive. For lip balms hydrated in 150 mM NaCl (ionic strength of human saliva), XDLVO calculations predict that hydrophilic colloids (MS2, P22, SiO2) may attach into shallow secondary minima. Due to the relative hydrophobicity of human adenoviruses, primary maxima in XDLVO profiles are low or non-existent making irreversible deposition into primary energy minima possible. Preliminary QCM-D tests with SiO2 colloids and HAdV5 confirm deposition on hydrated lip balms.",

keywords = "Adenovirus, Adhesion, Fomites, Lip balm, Lipstick, Personal care products, Public health, QCM-D, Virus transfer, XDLVO",

author = "Xunhao Wang and Reyhan {\c S}eng{\"u}r-Ta{\c s}demir and İsmail Koyuncu and Tarabara, \{Volodymyr V.\}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2021",

month = jan,

day = "1",

doi = "10.1016/j.jcis.2020.07.143",

language = "English",

volume = "581",

pages = "884--894",

journal = "Journal of Colloid and Interface Science",

issn = "0021-9797",

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T1 - Lip balm drying promotes virus attachment

T2 - Characterization of lip balm coatings and XDLVO modeling

AU - Wang, Xunhao

AU - Şengür-Taşdemir, Reyhan

AU - Koyuncu, İsmail

AU - Tarabara, Volodymyr V.

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Hypothesis: Drying-induced decrease in lip balm surface energy enhances virus adhesion due to the emergence of strong hydrophobic colloid-surface interactions. Experiments: A protocol was developed for preparing lip balm coatings to enable physicochemical characterization and adhesion studies. Surface charge and hydrophobicity of four brands of lip balm (dry and hydrated) and human adenovirus 5 (HAdV5) were measured and used to calculate the extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) energy of interactions between lip balm coatings and HAdV5 as well as four other colloids: HAdV40, MS2 and P22 bacteriophages, and SiO2. Quartz crystal microbalance with dissipation monitoring (QCM-D) tests employed SiO2 colloids, HAdV5 and hydrated lip balms. Findings: Drying of lip balms results in a dramatic decrease of their surface energy (δΔGsws≥ 83.0 mJ/m2) making the surfaces highly hydrophobic. For dry lip balms, the interaction of the balm surface with all five colloids is attractive. For lip balms hydrated in 150 mM NaCl (ionic strength of human saliva), XDLVO calculations predict that hydrophilic colloids (MS2, P22, SiO2) may attach into shallow secondary minima. Due to the relative hydrophobicity of human adenoviruses, primary maxima in XDLVO profiles are low or non-existent making irreversible deposition into primary energy minima possible. Preliminary QCM-D tests with SiO2 colloids and HAdV5 confirm deposition on hydrated lip balms.

AB - Hypothesis: Drying-induced decrease in lip balm surface energy enhances virus adhesion due to the emergence of strong hydrophobic colloid-surface interactions. Experiments: A protocol was developed for preparing lip balm coatings to enable physicochemical characterization and adhesion studies. Surface charge and hydrophobicity of four brands of lip balm (dry and hydrated) and human adenovirus 5 (HAdV5) were measured and used to calculate the extended Derjaguin-Landau-Verwey-Overbeek (XDLVO) energy of interactions between lip balm coatings and HAdV5 as well as four other colloids: HAdV40, MS2 and P22 bacteriophages, and SiO2. Quartz crystal microbalance with dissipation monitoring (QCM-D) tests employed SiO2 colloids, HAdV5 and hydrated lip balms. Findings: Drying of lip balms results in a dramatic decrease of their surface energy (δΔGsws≥ 83.0 mJ/m2) making the surfaces highly hydrophobic. For dry lip balms, the interaction of the balm surface with all five colloids is attractive. For lip balms hydrated in 150 mM NaCl (ionic strength of human saliva), XDLVO calculations predict that hydrophilic colloids (MS2, P22, SiO2) may attach into shallow secondary minima. Due to the relative hydrophobicity of human adenoviruses, primary maxima in XDLVO profiles are low or non-existent making irreversible deposition into primary energy minima possible. Preliminary QCM-D tests with SiO2 colloids and HAdV5 confirm deposition on hydrated lip balms.

KW - Adenovirus

KW - Adhesion

KW - Fomites

KW - Lip balm

KW - Lipstick

KW - Personal care products

KW - Public health

KW - QCM-D

KW - Virus transfer

KW - XDLVO

UR - https://www.scopus.com/pages/publications/85089946624

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DO - 10.1016/j.jcis.2020.07.143

M3 - Article

C2 - 32877879

AN - SCOPUS:85089946624

SN - 0021-9797

VL - 581

SP - 884

EP - 894

JO - Journal of Colloid and Interface Science

JF - Journal of Colloid and Interface Science

ER -

Lip balm drying promotes virus attachment: Characterization of lip balm coatings and XDLVO modeling

Abstract

Bibliographical note

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Keywords

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