Light dosimetry: effects of dehydration and thermal damage on the optical properties of the human aorta

Inci F. Çilesiz, Ashley J. Welch

Research output: Contribution to journalArticlepeer-review

105 Citations (Scopus)

Abstract

The influences of dehydration and thermal damage on in vitro optical properties of human aorta were studied. The absorption coefficient increased by 20-50%, especially in the visible range when at least 40% of total tissue weight was lost as a result of dehydration. The reduced scattering coefficientincreased by 10-45 in the visible and 30% to over 150% in the near IR after the tissue samples were heated in a constant temperature water bathat 1000°C for 300±10 s. This study implies that dehydration and protein coagulation during photothermal treatment of tissue are important factors altering optical properties of tissue.

Original languageEnglish
Pages (from-to)477-487
Number of pages11
JournalApplied Optics
Volume32
Issue number4
DOIs
Publication statusPublished - Feb 1993
Externally publishedYes

Keywords

  • Dosimetry
  • Hydration
  • Optical properties
  • Protein coagulation
  • Spectrophotometer

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