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Inhibitors of Apoptosis Proteins and IL-1β: A Tangled Relationship

  • Ceren Ciraci
  • , Fayyaz S. Sutterwala*
  • *Corresponding author for this work
  • University of Iowa
  • Department of Veterans Affairs

Research output: Contribution to journalShort surveypeer-review

2 Citations (Scopus)

Abstract

Inhibitors of apoptosis proteins (IAPs) are important regulators of both cell death and inflammation. In this issue of Immunity, Vince et al. (2012) report that inhibition of IAPs results in the processing and secretion of IL-1β through RIP3-mediated caspase-1- and caspase-8-dependent pathways.

Original languageEnglish
Pages (from-to)155-157
Number of pages3
JournalImmunity
Volume36
Issue number2
DOIs
Publication statusPublished - 24 Feb 2012
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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