Inhibitors of Apoptosis Proteins and IL-1β: A Tangled Relationship

Ceren Ciraci, Fayyaz S. Sutterwala*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

2 Citations (Scopus)

Abstract

Inhibitors of apoptosis proteins (IAPs) are important regulators of both cell death and inflammation. In this issue of Immunity, Vince et al. (2012) report that inhibition of IAPs results in the processing and secretion of IL-1β through RIP3-mediated caspase-1- and caspase-8-dependent pathways.

Original languageEnglish
Pages (from-to)155-157
Number of pages3
JournalImmunity
Volume36
Issue number2
DOIs
Publication statusPublished - 24 Feb 2012
Externally publishedYes

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