Identification and modelling of aerobic hydrolysis - Application of optimal experimental design

Güçlü Insel*, Derin Orhon, Peter A. Vanrolleghem

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

98 Citations (Scopus)

Abstract

Hydrolysis mechanism plays a dominant role in the delicate balance of electron donor/electron acceptor ratios in BNR and EBPR systems as an important carbon source. In this study, the surface-saturation-type hydrolysis kinetics was investigated based on respirometric measurements, within the context of the theoretical and the practical identifiability of mathematical models. The identifiable parameters of a selected model were derived from respirograms. In addition, the information from the experiments was evaluated on the basis of Optimal Experimental Design (OED) methodology for different initial conditions of the batch respirometric experiment.

Original languageEnglish
Pages (from-to)437-445
Number of pages9
JournalJournal of Chemical Technology and Biotechnology
Volume78
Issue number4
DOIs
Publication statusPublished - 1 Apr 2003

Keywords

  • Hyrolysis kinetics
  • Modelling
  • Optimal Experimental Design (OED)
  • Practical identifiability
  • Respirometry
  • Theoretical identifiability

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