Hsp70 Chaperone Ligands Control Domain Association via an Allosteric Mechanism Mediated by the Interdomain Linker

Keyphrases

• Control Domain 100%
• Hsp70 Chaperone 100%
• Interdomain Linker 100%
• Substrate-binding Domain 100%
• Ligand-controlled 100%
• Allosteric Mechanism 100%
• Domain Association 100%
• ATP Binding 66%
• DnaK 66%
• Escherichia Coli 33%
• Conformational Change 33%
• ATP Synthase 33%
• Protein Membrane 33%
• Heat Shock Protein 70 (HSP70) 33%
• Single Domain 33%
• Stable Interface 33%
• Membrane Translocation 33%
• Protein Disaggregation 33%
• Protein Folding 33%
• Allosteric Coupling 33%
• Nucleotide-binding Domain 33%
• Inter-domain Communication 33%
• Substrate Binding Site 33%
• Substrate Binding 33%
• Substrate Proteins 33%
• Two-component Domains 33%

Biochemistry, Genetics and Molecular Biology

• Hsp70 100%
• Adenosine Triphosphate 100%
• Binding Domain 60%
• Conformational Change 20%
• Protein Folding 20%
• Binding Site 20%
• Escherichia coli 20%
• Adenosine Diphosphate 20%
• ATPase 20%