High-throughput cell sorter with piezoelectric actuation

C. H. Chen, Sung H. Cho, A. Erten, Y. H. Lo

Research output: Contribution to conferencePaperpeer-review

3 Citations (Scopus)

Abstract

Currently, most of the integrated sorting modules in the microfabricated DEPbased and fluorescent-activated cell sorters (μFACS) still suffer from lowthroughput operation and require complex fabrication process (e.g. embedded electrodes) and high power consumption (e.g. electrokinetically-driven sorters). In this paper, we demonstrate an easy-to-fabricate, low-powered and high-speed sorting module (at a single cell level) using an on-chip integrated piezoelectric (PZT) actuator. By controlling the bending motion of the PZT actuator, we have investigated and verified the high-speed flow-switching and sorting capabilities both theoretically (dynamic simulation) and experimentally using beads and biological agents.

Original languageEnglish
Pages155-157
Number of pages3
Publication statusPublished - 2008
Externally publishedYes
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: 12 Oct 200816 Oct 2008

Conference

Conference12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/TerritoryUnited States
CitySan Diego, CA
Period12/10/0816/10/08

Keywords

  • Hydrodynamic
  • Microfluidics
  • Piezoelectric
  • Sorting

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