Hematoxylin ve Eosin resimlerinde ana yapilarin bölütlenmesi

Translated title of the contribution: Segmentation of the main structures in Hematoxylin and Eosin images

Sercan Cayir, Ercan Alp Serteli, Samet Ayalti, Sukru Burak Cetin, Gokhan Hatipoglu, Mustafa Kamasak, Cisem Yazici, Salar Razavi, Fariba D. Khameneh, Imam Samil Yetik, Ekrem Cihad Cetin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Citations (Scopus)

Abstract

Pathologists conduct a biopsy on a tissue when a carcinoma case for a patient is suspected. They stain the cells on that tissue using some biochemical materials that react with a certain cell element. They put stained cells onto a slide and examine the cells by using an optical microscope device. In our case, we will focus on H&E stained breast tissue samples. Pathologists keep track of a standard process to determine the patient's condition by focusing on the structures in H&E stained images such as epithelium, lumen, and nuclei. They employ scoring methods with quantitative and qualitative inferences in this decision process. Those inferences contain mitotic nuclei activity, number of the nucleus, lumen region distribution, epithelium area size and so on. Each factor has a score for the patient's carcinoma case. In this paper a novel image processing algorithm is developed to enable the pathologists to make decisions easily by segmenting epithelium, lumen and nuclei structures. Actual microscopic images could show some degenerated cell structures because of staining variability and some artifacts. Our algorithm demonstrates the structures clearly while colorizing them with distinctive colors considering their transparency.

Translated title of the contributionSegmentation of the main structures in Hematoxylin and Eosin images
Original languageTurkish
Title of host publication26th IEEE Signal Processing and Communications Applications Conference, SIU 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1-4
Number of pages4
ISBN (Electronic)9781538615010
DOIs
Publication statusPublished - 5 Jul 2018
Event26th IEEE Signal Processing and Communications Applications Conference, SIU 2018 - Izmir, Turkey
Duration: 2 May 20185 May 2018

Publication series

Name26th IEEE Signal Processing and Communications Applications Conference, SIU 2018

Conference

Conference26th IEEE Signal Processing and Communications Applications Conference, SIU 2018
Country/TerritoryTurkey
CityIzmir
Period2/05/185/05/18

Bibliographical note

Publisher Copyright:
© 2018 IEEE.

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