TY - JOUR
T1 - Frontiers in conventional and nanomaterials based electrochemical sensing and biosensing approaches for Ochratoxin A analysis in foodstuffs
T2 - A review
AU - Khataee, Alireza
AU - Sohrabi, Hessamaddin
AU - Arbabzadeh, Omid
AU - Khaaki, Pegah
AU - Majidi, Mir Reza
N1 - Publisher Copyright:
© 2021 Elsevier Ltd
PY - 2021/3
Y1 - 2021/3
N2 - Highly sensitive and rapid methods for the Ochratoxin A (OTA) detection as a main class of Ochratoxins (OT) in various food samples is significant. In the present review, novel OTA detection techniques based on electrochemical and conventional methods have been extensively explained, and also compared with each other in food samples. We classified the various electrochemical based techniques of OTA determination creatively into Impedimetric, Voltammetric, Amperometric and Electrochemiluminescence assays and their efficient comparison with conventional, and clinical methods including Capillary Electrophoresis (CE), High Performance Liquid Chromatography (HPLC), Liquid Chromatography/Mass Spectroscopy (LC/MS), and Enzyme Linked Immunosorbent Assay (ELISA) has been performed comprehensively. Moreover, structure, characteristics, and different types of OT and OTA are explained as extensively as possible. A summary of the current limitations and future challenges in OTA analysis are described, which efficiently provide a pathway for further developments and applications.
AB - Highly sensitive and rapid methods for the Ochratoxin A (OTA) detection as a main class of Ochratoxins (OT) in various food samples is significant. In the present review, novel OTA detection techniques based on electrochemical and conventional methods have been extensively explained, and also compared with each other in food samples. We classified the various electrochemical based techniques of OTA determination creatively into Impedimetric, Voltammetric, Amperometric and Electrochemiluminescence assays and their efficient comparison with conventional, and clinical methods including Capillary Electrophoresis (CE), High Performance Liquid Chromatography (HPLC), Liquid Chromatography/Mass Spectroscopy (LC/MS), and Enzyme Linked Immunosorbent Assay (ELISA) has been performed comprehensively. Moreover, structure, characteristics, and different types of OT and OTA are explained as extensively as possible. A summary of the current limitations and future challenges in OTA analysis are described, which efficiently provide a pathway for further developments and applications.
KW - Electrochemical methods
KW - Food toxicity
KW - Mycotoxin
KW - Sensing and biosensing assays
UR - http://www.scopus.com/inward/record.url?scp=85100579657&partnerID=8YFLogxK
U2 - 10.1016/j.fct.2021.112030
DO - 10.1016/j.fct.2021.112030
M3 - Article
C2 - 33548373
AN - SCOPUS:85100579657
SN - 0278-6915
VL - 149
JO - Food and Chemical Toxicology
JF - Food and Chemical Toxicology
M1 - 112030
ER -