Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi

Emre Kayan; Tarik Kavusan; Sevgi Önal; Devrim P. Okvur; Özden Y. Özuysal; Behçet Ugur Töreyin; Devrim Ünay

doi:10.1109/TIPTEKNO50054.2020.9299319

Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi

Translated title of the contribution: A Preliminary Study on Cell Motility Analysis from Phase-Contrast Microscopy Image Series

Emre Kayan, Tarik Kavusan, Sevgi Önal, Devrim P. Okvur, Özden Y. Özuysal, Behçet Ugur Töreyin, Devrim Ünay

Informatics Institute

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

Analyses of morphology, polarity, and motility of cells is important for cell biology research such as metastatic and invasive capacity of cells, wound healing, and embryonic development. Automation of such analyses using image series of phase-contrast optical microscopy, which allows label-free imaging of live cells in their living environment, is a need. With this purpose, in this study image series of a cell motility experiment is manually annotated, and an automation algorithm realizing motion and shape analyses of cells using the annotated data is developed. In addition, due to the low number of annotated data at hand, a U-Net based solution is devised for automated segmentation of the cells and its performance is evaluated.

Translated title of the contribution	A Preliminary Study on Cell Motility Analysis from Phase-Contrast Microscopy Image Series
Original language	Turkish
Title of host publication	TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781728180731
DOIs	https://doi.org/10.1109/TIPTEKNO50054.2020.9299319
Publication status	Published - 19 Nov 2020
Event	2020 Medical Technologies Congress, TIPTEKNO 2020 - Antalya, Turkey Duration: 19 Nov 2020 → 20 Nov 2020

Publication series

Name	TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020

Conference

Conference	2020 Medical Technologies Congress, TIPTEKNO 2020
Country/Territory	Turkey
City	Antalya
Period	19/11/20 → 20/11/20

Bibliographical note

Publisher Copyright:
© 2020 IEEE.

Access to Document

10.1109/TIPTEKNO50054.2020.9299319

Cite this

Kayan, E., Kavusan, T., Önal, S., Okvur, D. P., Özuysal, Ö. Y., Töreyin, B. U., & Ünay, D. (2020). Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi. In TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020 Article 9299319 (TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TIPTEKNO50054.2020.9299319

Kayan, Emre ; Kavusan, Tarik ; Önal, Sevgi et al. / Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi. TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020. Institute of Electrical and Electronics Engineers Inc., 2020. (TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020).

@inproceedings{9b086e7977994a6199a01dd5cc16aa47,

title = "Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi",

abstract = "Analyses of morphology, polarity, and motility of cells is important for cell biology research such as metastatic and invasive capacity of cells, wound healing, and embryonic development. Automation of such analyses using image series of phase-contrast optical microscopy, which allows label-free imaging of live cells in their living environment, is a need. With this purpose, in this study image series of a cell motility experiment is manually annotated, and an automation algorithm realizing motion and shape analyses of cells using the annotated data is developed. In addition, due to the low number of annotated data at hand, a U-Net based solution is devised for automated segmentation of the cells and its performance is evaluated.",

keywords = "cell motility, deep learning, image processing, phase-contrast optical microscopy",

author = "Emre Kayan and Tarik Kavusan and Sevgi {\"O}nal and Okvur, {Devrim P.} and {\"O}zuysal, {{\"O}zden Y.} and T{\"o}reyin, {Beh{\c c}et Ugur} and Devrim {\"U}nay",

note = "Publisher Copyright: {\textcopyright} 2020 IEEE.; 2020 Medical Technologies Congress, TIPTEKNO 2020 ; Conference date: 19-11-2020 Through 20-11-2020",

year = "2020",

month = nov,

day = "19",

doi = "10.1109/TIPTEKNO50054.2020.9299319",

language = "T{\"u}rk{\c c}e",

series = "TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

booktitle = "TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020",

address = "United States",

}

Kayan, E, Kavusan, T, Önal, S, Okvur, DP, Özuysal, ÖY, Töreyin, BU & Ünay, D 2020, Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi. in TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020., 9299319, TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020, Institute of Electrical and Electronics Engineers Inc., 2020 Medical Technologies Congress, TIPTEKNO 2020, Antalya, Turkey, 19/11/20. https://doi.org/10.1109/TIPTEKNO50054.2020.9299319

Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi. / Kayan, Emre; Kavusan, Tarik; Önal, Sevgi et al.
TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020. Institute of Electrical and Electronics Engineers Inc., 2020. 9299319 (TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi

AU - Kayan, Emre

AU - Kavusan, Tarik

AU - Önal, Sevgi

AU - Okvur, Devrim P.

AU - Özuysal, Özden Y.

AU - Töreyin, Behçet Ugur

AU - Ünay, Devrim

PY - 2020/11/19

Y1 - 2020/11/19

N2 - Analyses of morphology, polarity, and motility of cells is important for cell biology research such as metastatic and invasive capacity of cells, wound healing, and embryonic development. Automation of such analyses using image series of phase-contrast optical microscopy, which allows label-free imaging of live cells in their living environment, is a need. With this purpose, in this study image series of a cell motility experiment is manually annotated, and an automation algorithm realizing motion and shape analyses of cells using the annotated data is developed. In addition, due to the low number of annotated data at hand, a U-Net based solution is devised for automated segmentation of the cells and its performance is evaluated.

AB - Analyses of morphology, polarity, and motility of cells is important for cell biology research such as metastatic and invasive capacity of cells, wound healing, and embryonic development. Automation of such analyses using image series of phase-contrast optical microscopy, which allows label-free imaging of live cells in their living environment, is a need. With this purpose, in this study image series of a cell motility experiment is manually annotated, and an automation algorithm realizing motion and shape analyses of cells using the annotated data is developed. In addition, due to the low number of annotated data at hand, a U-Net based solution is devised for automated segmentation of the cells and its performance is evaluated.

KW - cell motility

KW - deep learning

KW - image processing

KW - phase-contrast optical microscopy

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U2 - 10.1109/TIPTEKNO50054.2020.9299319

DO - 10.1109/TIPTEKNO50054.2020.9299319

M3 - Konferans katkısı

AN - SCOPUS:85099471929

T3 - TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020

BT - TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2020 Medical Technologies Congress, TIPTEKNO 2020

Y2 - 19 November 2020 through 20 November 2020

ER -

Kayan E, Kavusan T, Önal S, Okvur DP, Özuysal ÖY, Töreyin BU et al. Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi. In TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020. Institute of Electrical and Electronics Engineers Inc. 2020. 9299319. (TIPTEKNO 2020 - Tip Teknolojileri Kongresi - 2020 Medical Technologies Congress, TIPTEKNO 2020). doi: 10.1109/TIPTEKNO50054.2020.9299319

Faz-Kontrast Mikroskopi Goruntu Serilerinden Hucre Hareketliligi Analizi On-Calismasi

Abstract

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