EPR investigation of gamma-irradiated FAMOSER drug for DOSIMETRIC purposes

Nazrin Babayeva; Emel Ece; Recep Biyik; Ayhan Ozmen; Ulku Sayin

doi:10.1093/rpd/ncad041

EPR investigation of gamma-irradiated FAMOSER drug for DOSIMETRIC purposes

Nazrin Babayeva^*, Emel Ece, Recep Biyik, Ayhan Ozmen, Ulku Sayin

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Exposure to ionizing radiation can also lead to the formation of stable or unstable radicals in the structures of drugs, as in many materials. The concentrations of these radicals may show a linear dependence on the radiation dose exposed. Since drugs are materials that can be found next to or on radiation victims during a possible nuclear or radiological accident, it is very meaningful to determine the Electron Paramagnetic Resonance (EPR) dosimetric properties of stable radicals in their structures. In this study, the dosimetric properties of Famoser, which is one of the stomach-relieving drugs that people often have with them in their daily life, in the dose range of 10-800 Gy were investigated by EPR technique.

Original language	English
Pages (from-to)	1520-1525
Number of pages	6
Journal	Radiation Protection Dosimetry
Volume	199
Issue number	14
DOIs	https://doi.org/10.1093/rpd/ncad041
Publication status	Published - 1 Sept 2023
Externally published	Yes

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© The Author(s) 2023. Published by Oxford University Press. All rights reserved.

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abstract = "Exposure to ionizing radiation can also lead to the formation of stable or unstable radicals in the structures of drugs, as in many materials. The concentrations of these radicals may show a linear dependence on the radiation dose exposed. Since drugs are materials that can be found next to or on radiation victims during a possible nuclear or radiological accident, it is very meaningful to determine the Electron Paramagnetic Resonance (EPR) dosimetric properties of stable radicals in their structures. In this study, the dosimetric properties of Famoser, which is one of the stomach-relieving drugs that people often have with them in their daily life, in the dose range of 10-800 Gy were investigated by EPR technique.",

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AU - Ozmen, Ayhan

AU - Sayin, Ulku

PY - 2023/9/1

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AB - Exposure to ionizing radiation can also lead to the formation of stable or unstable radicals in the structures of drugs, as in many materials. The concentrations of these radicals may show a linear dependence on the radiation dose exposed. Since drugs are materials that can be found next to or on radiation victims during a possible nuclear or radiological accident, it is very meaningful to determine the Electron Paramagnetic Resonance (EPR) dosimetric properties of stable radicals in their structures. In this study, the dosimetric properties of Famoser, which is one of the stomach-relieving drugs that people often have with them in their daily life, in the dose range of 10-800 Gy were investigated by EPR technique.

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EPR investigation of gamma-irradiated FAMOSER drug for DOSIMETRIC purposes

Abstract

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