Effects of lipid-based encapsulation on the bioaccessibility and bioavailability of phenolic compounds

Gulay Ozkan, Tina Kostka, Tuba Esatbeyoglu*, Esra Capanoglu

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

57 Citations (Scopus)


Phenolic compounds (quercetin, rutin, cyanidin, tangeretin, hesperetin, curcumin, resveratrol, etc.) are known to have health-promoting effects and they are accepted as one of the main proposed nutraceutical group. However, their application is limited owing to the problems related with their stability and water solubility as well as their low bioaccessibility and bioavailability. These limitations can be overcome by encapsulating phenolic compounds by physical, physicochemical and chemical encapsulation techniques. This review focuses on the effects of encapsulation, especially lipid-based techniques (emulsion/nanoemulsion, solid lipid nanoparticles, liposomes/nanoliposomes, etc.), on the digestibility characteristics of phenolic compounds in terms of bioaccessibility and bioavailability.

Original languageEnglish
Article number5545
Issue number23
Publication statusPublished - 1 Dec 2020

Bibliographical note

Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.


Funding: The publication of this article was funded by the Open Access Fund of the Leibniz Universität Hannover.

FundersFunder number
Gottfried Wilhelm Leibniz Universität Hannover


    • Bioaccessibility
    • Bioavailability
    • Curcumin
    • Encapsulation
    • Lipid-based delivery systems
    • PMF
    • Polyphenols
    • Resveratrol


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