Effects of a porphyrazine derivative on some developmental characteristics of Drosophila melanogaster

Ayla Karatas; Fatma Ertan; Neslihan Saki; Ensar Baspinar; A. Sevim; A. Gül

doi:10.1556/ABiol.62.2011.4.8

Effects of a porphyrazine derivative on some developmental characteristics of Drosophila melanogaster

Ayla Karatas^*, Fatma Ertan, Neslihan Saki, Ensar Baspinar, A. Sevim, A. Gül

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphyrazinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F ₁ and F ₂ generation of Drosophila. Although individuals of F2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.

Original language	English
Pages (from-to)	426-440
Number of pages	15
Journal	Acta Biologica Hungarica
Volume	62
Issue number	4
DOIs	https://doi.org/10.1556/ABiol.62.2011.4.8
Publication status	Published - 1 Dec 2011

Keywords

Drosophila melanogaster
egg fertility
Porphyrazine
sex ratio
toxic effect

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10.1556/ABiol.62.2011.4.8

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abstract = "In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphyrazinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F 1 and F 2 generation of Drosophila. Although individuals of F2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.",

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AU - Ertan, Fatma

AU - Saki, Neslihan

AU - Baspinar, Ensar

AU - Sevim, A.

AU - Gül, A.

PY - 2011/12/1

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AB - In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphyrazinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F 1 and F 2 generation of Drosophila. Although individuals of F2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.

KW - Drosophila melanogaster

KW - egg fertility

KW - Porphyrazine

KW - sex ratio

KW - toxic effect

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Effects of a porphyrazine derivative on some developmental characteristics of Drosophila melanogaster

Abstract

Keywords

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