Dynamical modeling and experimental aspects of multi-responsive hydroxy-functional methacrylate-based gels with tunable swelling induced by multivalent ions

Nermin Orakdogen*, Berran Sanay

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Novel materials displaying multi-responsive property were developed by forming crosslinked copolymer systems that exhibit distinct temperature, pH and salt-sensitivity independently. An investigation of the mechanical properties of a novel multi-responsive poly(hydroxypropyl methacrylate) (PHPMA)-based hydrogel system was carried out with two major objectives. First was to study the effect of various preparation conditions; reaction temperature, comonomer content on the elasticity as well as on the absorbency of resulting hydroxy-functional methacrylate-based gels and the second was to interpret their water uptake data by various kinetic models. Experiments were conducted to characterize the equilibrium swelling and temperature/pH-dependent phase transitions of PHPMA-based copolymeric gels prepared by radical crosslinking copolymerization in aqueous solution with tetraethyleneglycol dimethacrylate (TEGDMA) as crosslinker. The aqueous equilibrium swelling properties of PHPMA hydrogels and cryogels containing methacrylate-based comonomer were described using N,N-dimethylaminopropyl methacrylate (DMAEMA) having weakly basic cationic groups. For PHPMA-based copolymeric hydrogels, the scaling laws relating the optimum preparation conditions with the crosslinking density N and the swelling degree qv were derived. Dynamic kinetics profiles were evaluated to outline the swelling/deswelling response of the resulting hydrogels and cryogels which presents useful information when designing specific applications that pursue or require the absorption of pH-sensitive or ionic-strength-sensitive molecules.

Original languageEnglish
Pages (from-to)151-168
Number of pages18
JournalPolymer
Volume129
DOIs
Publication statusPublished - 27 Oct 2017

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Ltd

Funding

Financial support of this work from the Istanbul Technical University Research Fund (ITU, 39564 ) was gratefully acknowledged.

FundersFunder number
Istanbul Technical University Research Fund39564

    Keywords

    • Elasticity
    • Hydroxypropyl methacrylate
    • N,N-dimethylaminopropyl methacrylate
    • Swelling

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