DNA and BSA binding studies of novel tetracationic phthalocyanines

Ramazan Öztürk; Şaban Kalay; Ayfer Kalkan; Ali Türkan; Mustafa F. Abasiyanik; Zehra Altuntaş Bayir; Ahmet Gül

doi:10.1142/S1088424608000315

DNA and BSA binding studies of novel tetracationic phthalocyanines

Ramazan Öztürk^*
, Şaban Kalay
, Ayfer Kalkan
, Ali Türkan
, Mustafa F. Abasiyanik
, Zehra Altuntaş Bayir
, Ahmet Gül

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

The novel tetracationic metallophthalocyanines having diethylmethyl aminoethylsulfanyl groups on the periphery have been synthesized and characterized. The compounds tend to form aggregates in aqueous solutions. The aggregation of ZnPc⁴⁺ or CoPc⁴⁺, but not that of CuPc ⁴⁺, was hindered by the addition of surfactants (Triton X-100 and Tween 20). Using absorption and fluorescence spectroscopic techniques, DNA and BSA binding properties of tetracationic ZnPc in the presence of the surfactants were also investigated.

Original language	English
Pages (from-to)	932-941
Number of pages	10
Journal	Journal of Porphyrins and Phthalocyanines
Volume	12
Issue number	8
DOIs	https://doi.org/10.1142/S1088424608000315
Publication status	Published - 2008

Funding

This study was supported by the Scientific and Technological Research Council of Turkey (TUBITAK) (Project No: 105T373)

Funders	Funder number
TUBITAK	105T373
Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Keywords

Cationic phthalocyanines
DNA binding
Phthalocyanine-BSA interaction
Phthalocyanine-DNA interaction

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10.1142/S1088424608000315

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title = "DNA and BSA binding studies of novel tetracationic phthalocyanines",

abstract = "The novel tetracationic metallophthalocyanines having diethylmethyl aminoethylsulfanyl groups on the periphery have been synthesized and characterized. The compounds tend to form aggregates in aqueous solutions. The aggregation of ZnPc4+ or CoPc4+, but not that of CuPc 4+, was hindered by the addition of surfactants (Triton X-100 and Tween 20). Using absorption and fluorescence spectroscopic techniques, DNA and BSA binding properties of tetracationic ZnPc in the presence of the surfactants were also investigated.",

keywords = "Cationic phthalocyanines, DNA binding, Phthalocyanine-BSA interaction, Phthalocyanine-DNA interaction",

author = "Ramazan {\"O}zt{\"u}rk and {\c S}aban Kalay and Ayfer Kalkan and Ali T{\"u}rkan and Abasiyanik, \{Mustafa F.\} and Bayir, \{Zehra Altunta{\c s}\} and Ahmet G{\"u}l",

year = "2008",

doi = "10.1142/S1088424608000315",

language = "English",

volume = "12",

pages = "932--941",

journal = "Journal of Porphyrins and Phthalocyanines",

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T1 - DNA and BSA binding studies of novel tetracationic phthalocyanines

AU - Öztürk, Ramazan

AU - Kalay, Şaban

AU - Kalkan, Ayfer

AU - Türkan, Ali

AU - Abasiyanik, Mustafa F.

AU - Bayir, Zehra Altuntaş

AU - Gül, Ahmet

PY - 2008

Y1 - 2008

N2 - The novel tetracationic metallophthalocyanines having diethylmethyl aminoethylsulfanyl groups on the periphery have been synthesized and characterized. The compounds tend to form aggregates in aqueous solutions. The aggregation of ZnPc4+ or CoPc4+, but not that of CuPc 4+, was hindered by the addition of surfactants (Triton X-100 and Tween 20). Using absorption and fluorescence spectroscopic techniques, DNA and BSA binding properties of tetracationic ZnPc in the presence of the surfactants were also investigated.

AB - The novel tetracationic metallophthalocyanines having diethylmethyl aminoethylsulfanyl groups on the periphery have been synthesized and characterized. The compounds tend to form aggregates in aqueous solutions. The aggregation of ZnPc4+ or CoPc4+, but not that of CuPc 4+, was hindered by the addition of surfactants (Triton X-100 and Tween 20). Using absorption and fluorescence spectroscopic techniques, DNA and BSA binding properties of tetracationic ZnPc in the presence of the surfactants were also investigated.

KW - Cationic phthalocyanines

KW - DNA binding

KW - Phthalocyanine-BSA interaction

KW - Phthalocyanine-DNA interaction

UR - https://www.scopus.com/pages/publications/56849114351

U2 - 10.1142/S1088424608000315

DO - 10.1142/S1088424608000315

M3 - Article

AN - SCOPUS:56849114351

SN - 1088-4246

VL - 12

SP - 932

EP - 941

JO - Journal of Porphyrins and Phthalocyanines

JF - Journal of Porphyrins and Phthalocyanines

IS - 8

ER -

DNA and BSA binding studies of novel tetracationic phthalocyanines

Abstract

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Keywords

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