DNA and BSA binding studies of novel tetracationic phthalocyanines

Ramazan Öztürk*, Şaban Kalay, Ayfer Kalkan, Ali Türkan, Mustafa F. Abasiyanik, Zehra Altuntaş Bayir, Ahmet Gül

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

The novel tetracationic metallophthalocyanines having diethylmethyl aminoethylsulfanyl groups on the periphery have been synthesized and characterized. The compounds tend to form aggregates in aqueous solutions. The aggregation of ZnPc4+ or CoPc4+, but not that of CuPc 4+, was hindered by the addition of surfactants (Triton X-100 and Tween 20). Using absorption and fluorescence spectroscopic techniques, DNA and BSA binding properties of tetracationic ZnPc in the presence of the surfactants were also investigated.

Original languageEnglish
Pages (from-to)932-941
Number of pages10
JournalJournal of Porphyrins and Phthalocyanines
Volume12
Issue number8
DOIs
Publication statusPublished - 2008

Keywords

  • Cationic phthalocyanines
  • DNA binding
  • Phthalocyanine-BSA interaction
  • Phthalocyanine-DNA interaction

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