Determination of veterinary antibiotics in dairy manure slurry by LC-MS/MS

Mahbub Alam*, Osman Atilla Arikan, Ebubekir Yuksel, Murat Eyvaz, Ercan Gurbulak, Okan Gunaydin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Veterinary antibiotics are used in the dairy animal for therapeutic purposes to better absorb nutrients and treat different diseases. However, developments of resistance against veterinary antibiotics which is generally disposed into the agricultural lands have been reported as a considerable concern. Therefore, this study was conducted to determine the veterinary antibiotics in dairy manure slurry obtained from three selected farms in various districts in the Marmara Region of Turkey. This study examined the quantification of monensin, lincomycin, amprolium and salinomycin in dairy manure samples by a liquid chromatography triple quadrupole mass spectrometry (LC-MS/MS). Atmospheric pressure ionization-tandem mass spectrometry was utilized on a benchtop triple quadrupole mass spectrometer operated in electrospray ionization (ESI) mode to analyze manure slurry samples. The procedures of the extraction and recovery studies were also stated.

Original languageEnglish
Pages (from-to)555-562
Number of pages8
JournalJournal of Liquid Chromatography and Related Technologies
Volume42
Issue number17-18
DOIs
Publication statusPublished - 8 Nov 2019

Bibliographical note

Publisher Copyright:
© 2019, © 2019 Taylor & Francis Group, LLC.

Funding

The authors express their appreciation to the SUMER laboratory (Gebze Technical University/Turkey) for their kind support to do LC-MS/MS analysis.

FundersFunder number
Gebze Technical University/Turkey

    Keywords

    • Dairy manure slurry
    • LC-MS/MS
    • veterinary antibiotics

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