Determination of dexamethasone by flow-injection chemiluminescence method using capped CdS quantum dots

Alireza Khataee; Aliyeh Hasanzadeh; Roya Lotfi; Rahmatollah Pourata; Sang Woo Joo

doi:10.1016/j.saa.2015.05.047

Determination of dexamethasone by flow-injection chemiluminescence method using capped CdS quantum dots

Alireza Khataee^*, Aliyeh Hasanzadeh, Roya Lotfi, Rahmatollah Pourata, Sang Woo Joo

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

l-Cysteine capped CdS quantum dots (QDs) were synthesized through a facile hydrothermal method and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), photoluminescence (PL) and UV-Vis spectroscopy. The light emitted from KMnO₄-l-cysteine capped CdS QDs reaction in acidic medium was applied as a simple and sensitive chemiluminescence (CL) system for determination of dexamethasone. The CL intensity of KMnO₄-l-cysteine capped CdS QDs CL system was remarkably enhanced in the presence of dexamethasone. Under optimum experimental conditions, the enhanced CL intensity was related to dexamethasone concentration in the range of 0.004-25.0 mg L^-1, with the detection limit (3σ) of 0.0013 mg L^-1. The analytical applicability of the proposed CL system was assessed by determining dexamethasone in spiked environmental water samples and pharmaceutical formulation. The analytical performances of proposed flow-injection CL method for the determination of dexamethasone were compared with those obtained by corona discharge ionization ion mobility spectrometry (CD-IMS) method. The proposed CL system exhibits a higher sensitivity and precision than the CD-IMS method for the determination of dexamethasone.

Original language	English
Pages (from-to)	63-71
Number of pages	9
Journal	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume	150
DOIs	https://doi.org/10.1016/j.saa.2015.05.047
Publication status	Published - 1 Jun 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
©2015 Elsevier B.V. All rights reserved.

Keywords

CdS quantum dots
Chemiluminescence
Dexamethasone
Flow injection
Nanocatalyst

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10.1016/j.saa.2015.05.047

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title = "Determination of dexamethasone by flow-injection chemiluminescence method using capped CdS quantum dots",

abstract = "l-Cysteine capped CdS quantum dots (QDs) were synthesized through a facile hydrothermal method and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), photoluminescence (PL) and UV-Vis spectroscopy. The light emitted from KMnO4-l-cysteine capped CdS QDs reaction in acidic medium was applied as a simple and sensitive chemiluminescence (CL) system for determination of dexamethasone. The CL intensity of KMnO4-l-cysteine capped CdS QDs CL system was remarkably enhanced in the presence of dexamethasone. Under optimum experimental conditions, the enhanced CL intensity was related to dexamethasone concentration in the range of 0.004-25.0 mg L-1, with the detection limit (3σ) of 0.0013 mg L-1. The analytical applicability of the proposed CL system was assessed by determining dexamethasone in spiked environmental water samples and pharmaceutical formulation. The analytical performances of proposed flow-injection CL method for the determination of dexamethasone were compared with those obtained by corona discharge ionization ion mobility spectrometry (CD-IMS) method. The proposed CL system exhibits a higher sensitivity and precision than the CD-IMS method for the determination of dexamethasone.",

keywords = "CdS quantum dots, Chemiluminescence, Dexamethasone, Flow injection, Nanocatalyst",

author = "Alireza Khataee and Aliyeh Hasanzadeh and Roya Lotfi and Rahmatollah Pourata and Joo, {Sang Woo}",

year = "2015",

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doi = "10.1016/j.saa.2015.05.047",

language = "English",

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journal = "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",

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T1 - Determination of dexamethasone by flow-injection chemiluminescence method using capped CdS quantum dots

AU - Khataee, Alireza

AU - Hasanzadeh, Aliyeh

AU - Lotfi, Roya

AU - Pourata, Rahmatollah

AU - Joo, Sang Woo

PY - 2015/6/1

Y1 - 2015/6/1

N2 - l-Cysteine capped CdS quantum dots (QDs) were synthesized through a facile hydrothermal method and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), photoluminescence (PL) and UV-Vis spectroscopy. The light emitted from KMnO4-l-cysteine capped CdS QDs reaction in acidic medium was applied as a simple and sensitive chemiluminescence (CL) system for determination of dexamethasone. The CL intensity of KMnO4-l-cysteine capped CdS QDs CL system was remarkably enhanced in the presence of dexamethasone. Under optimum experimental conditions, the enhanced CL intensity was related to dexamethasone concentration in the range of 0.004-25.0 mg L-1, with the detection limit (3σ) of 0.0013 mg L-1. The analytical applicability of the proposed CL system was assessed by determining dexamethasone in spiked environmental water samples and pharmaceutical formulation. The analytical performances of proposed flow-injection CL method for the determination of dexamethasone were compared with those obtained by corona discharge ionization ion mobility spectrometry (CD-IMS) method. The proposed CL system exhibits a higher sensitivity and precision than the CD-IMS method for the determination of dexamethasone.

AB - l-Cysteine capped CdS quantum dots (QDs) were synthesized through a facile hydrothermal method and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), photoluminescence (PL) and UV-Vis spectroscopy. The light emitted from KMnO4-l-cysteine capped CdS QDs reaction in acidic medium was applied as a simple and sensitive chemiluminescence (CL) system for determination of dexamethasone. The CL intensity of KMnO4-l-cysteine capped CdS QDs CL system was remarkably enhanced in the presence of dexamethasone. Under optimum experimental conditions, the enhanced CL intensity was related to dexamethasone concentration in the range of 0.004-25.0 mg L-1, with the detection limit (3σ) of 0.0013 mg L-1. The analytical applicability of the proposed CL system was assessed by determining dexamethasone in spiked environmental water samples and pharmaceutical formulation. The analytical performances of proposed flow-injection CL method for the determination of dexamethasone were compared with those obtained by corona discharge ionization ion mobility spectrometry (CD-IMS) method. The proposed CL system exhibits a higher sensitivity and precision than the CD-IMS method for the determination of dexamethasone.

KW - CdS quantum dots

KW - Chemiluminescence

KW - Dexamethasone

KW - Flow injection

KW - Nanocatalyst

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JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

ER -

Determination of dexamethasone by flow-injection chemiluminescence method using capped CdS quantum dots

Abstract

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