Design and fabrication of a new nonwoven-textile based platform for biosensor construction

Gülҫin Baysal, Sakip Önder, Ikilem Göcek, Levent Trabzon, Hüseyin Kizil, Fatma Neşe Kök, Burҫak Karagüzel Kayaoʇlu

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

This study focuses on the fabrication of a novel, flexible and disposable textile based biosensing platform by the use of an absorbent microfibrous nonwoven substrate as the base material. This platform was fabricated via photolithography technique. Physical barriers were designed using a hydrophobic photo-resist polymer which defined the liquid penetration pathways on the fabric surface. A good hydrophilic/hydrophobic contrast of the fabricated patterns on the fabric and a well-controlled liquid capillary penetration was achieved in the patterns. The potential of the system was tested by constructing an enzyme biosensor based on colorimetric detection of hydrogen peroxide. To obtain a more enhanced and reproducible signal, the reservoirs were modified with gelatin and a linear working range of 0.1-0.6 μM H 2 O 2 was obtained. The system could work on temperatures as high as 50°C without any loss in the signal and in a pH range of 3.0-7.0. This bio-sensing platform may later be combined by H 2 O 2 producing oxidases such as glucose oxidase, lactate oxidase, etc. and used for the rapid detection of various kinds of important analytes.

Original languageEnglish
Pages (from-to)475-484
Number of pages10
JournalSensors and Actuators, B: Chemical
Volume208
DOIs
Publication statusPublished - 1 Mar 2015

Bibliographical note

Publisher Copyright:
© 2014 Elsevier B.V. All rights reserved.

Funding

The authors would like to acknowledge the financial support provided by the Scientific and Technological Research Council of Turkey (TUBITAK) under Grant No. 111M483 . Authors acknowledge the assistance provided by Beren Şen and Ayşe B. Özdabak.

FundersFunder number
TUBITAK111M483
Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

    Keywords

    • Colorimetric detection
    • Enzyme biosensor
    • Fabrication
    • Hydrogen peroxide
    • Nonwoven
    • Photolithography

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