Degradation of oxytetracycline and its impacts on biogas-producing microbial community structure

Halil Coban*, Emine Ertekin, Orhan Ince, Gokhan Turker, Çağrı Akyol, Bahar Ince

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

The effect of veterinary antibiotics in anaerobic digesters is a concern where methane production efficiency is highly dependent on microbial community structure. In this study, both anaerobic degradation of a common veterinary antibiotic, oxytetracycline (OTC), and its effects on an anaerobic digester microbial community were investigated. Qualitative and quantitative molecular tools were used to monitor changes in microbial community structure during a 60-day batch incubation period of cow manure with the addition of different concentrations of the antibiotic. Molecular data were interpreted by a further redundancy analysis as a multivariate statistics approach. At the end of the experiment, approximately 48, 33, and 17 % of the initially added 50, 100, and 200 mg l−1 of OTC was still present in the serum bottles which reduced the biogas production via accumulation of some of the volatile fatty acids (VFAs). Biogas production was highly correlated with Methanobacteriales and Methanosarcinales gene copy numbers, and those parameters were negatively affected with oxytetracycline and VFA concentrations.

Original languageEnglish
Pages (from-to)1051-1060
Number of pages10
JournalBioprocess and Biosystems Engineering
Volume39
Issue number7
DOIs
Publication statusPublished - 1 Jul 2016

Bibliographical note

Publisher Copyright:
© 2016, Springer-Verlag Berlin Heidelberg.

Funding

We appreciate the grants from the Scientific and Technical Research Council of Turkey (TUBITAK, Project No: 109Y275). The authors are grateful to the Pharmacology and Toxicology Department of Istanbul University, Faculty of Veterinary Medicine for providing cow manure, A. M. Detweiler and L. M. Tom for English proofreading, and two anonymous reviewers for improving the scientific quality of the manuscript.

FundersFunder number
TUBITAK109Y275
Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

    Keywords

    • Biogas
    • Microbial community
    • Oxytetracycline
    • Real-time PCR

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