D2-dopamin reseptörlerinin PET ile görüntülenmesi

Translated title of the contribution: Imaging D2-dopamine receptor using PET

Mustafa E. Kamasak, Charles A. Bouman, Bradley T. Christian, Evan D. Morris

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this paper, we demonstrate how to form images of D2-dopamine receptor concentration in the brain with positron emission tomography (PET). The signal-to-noise ratio (SNR) of the reconstructed dynamic PET verileri is generally so low that region of interest (ROI) analysis is required to have accurate quantification. ROI analysis produces a single value of receptor concentration for each region in the brain. Elimination of intermediate reconstruction steps and direct reconstruction of parameters from sinograms allowed us to form dense images of parameters of interest [I]. In this paper, we applied the direct parametric reconstruction algorithm to form images of D2-dopamine receptor concentration within monkey brain using 18F-fallypride radiotracer. Our initial investigations show that our D2 receptor images are consistent with the results of the classical ROI analysis.

Translated title of the contributionImaging D2-dopamine receptor using PET
Original languageTurkish
Title of host publication2007 IEEE 15th Signal Processing and Communications Applications, SIU
DOIs
Publication statusPublished - 2007
Event2007 IEEE 15th Signal Processing and Communications Applications, SIU - Eskisehir, Turkey
Duration: 11 Jun 200713 Jun 2007

Publication series

Name2007 IEEE 15th Signal Processing and Communications Applications, SIU

Conference

Conference2007 IEEE 15th Signal Processing and Communications Applications, SIU
Country/TerritoryTurkey
CityEskisehir
Period11/06/0713/06/07

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