Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives

A. S. Demir; I. M. Akhmedov; Ö Şeşenoǧlu; O. Alptürk; S. Apaydin; Z. Gerçek; N. Ibrahimzade

doi:10.1039/b008317h

Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives

A. S. Demir^*
, I. M. Akhmedov
, Ö Şeşenoǧlu
, O. Alptürk
, S. Apaydin
, Z. Gerçek
, N. Ibrahimzade

^*Corresponding author for this work

Middle East Technical University

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.

Original language	English
Pages (from-to)	1162-1167
Number of pages	6
Journal	Journal of the Chemical Society, Perkin Transactions 1
Issue number	10
DOIs	https://doi.org/10.1039/b008317h
Publication status	Published - 2001
Externally published	Yes

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title = "Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives",

abstract = "The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.",

author = "Demir, \{A. S.\} and Akhmedov, \{I. M.\} and {\"O} {\c S}e{\c s}enoǧlu and O. Alpt{\"u}rk and S. Apaydin and Z. Ger{\c c}ek and N. Ibrahimzade",

year = "2001",

doi = "10.1039/b008317h",

language = "English",

pages = "1162--1167",

journal = "Journal of the Chemical Society, Perkin Transactions 1",

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publisher = "Chemical Society",

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TY - JOUR

T1 - Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives

AU - Demir, A. S.

AU - Akhmedov, I. M.

AU - Şeşenoǧlu, Ö

AU - Alptürk, O.

AU - Apaydin, S.

AU - Gerçek, Z.

AU - Ibrahimzade, N.

PY - 2001

Y1 - 2001

N2 - The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.

AB - The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.

UR - https://www.scopus.com/pages/publications/0034742935

U2 - 10.1039/b008317h

DO - 10.1039/b008317h

M3 - Article

AN - SCOPUS:0034742935

SN - 1472-7781

SP - 1162

EP - 1167

JO - Journal of the Chemical Society, Perkin Transactions 1

JF - Journal of the Chemical Society, Perkin Transactions 1

IS - 10

ER -

Conversion of homochiral amines, β-amino alcohols and α-amino acids to their chiral 2-substituted pyrrole derivatives

Abstract

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