Abstract
The results of a closed loop thermal feedback controlled laser-assisted tissue welding study in vivo are reported. A series of experiments was carried out to study and compare the weld strength and healing response of sutured and laser welded rat enterotomies with and without temperature feedback control (TFC) using a cryogenically cooled Ho:YAG laser. Although assignment of animals to three groups (control sutured, laser welded with and without TFC) and four observation periods (1, 3, 7, and 21 days) was randomized, several laser welded enterotomies without TFC had complications resulting in death of the animals. Those experiments were repeated. From the failure rates encountered, it is shown that TFC improves the quality of laser-assisted enterotomy closures.
| Original language | English |
|---|---|
| Pages (from-to) | 523-534 |
| Number of pages | 12 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 2395 |
| DOIs | |
| Publication status | Published - 12 May 1995 |
| Externally published | Yes |
| Event | Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V 1995 - San Jose, United States Duration: 1 Feb 1995 → 28 Feb 1995 |
Bibliographical note
Publisher Copyright:© SPIE 1995. All rights reserved.
Funding
This work was supported in part by the Department of Energy grant number DE-FGO5-91 ER 617 226 and in part by Albert and Clemmie Caster Foundation.
| Funders | Funder number |
|---|---|
| Albert and Clemmie Caster Foundation | |
| U.S. Department of Energy | DE-FGO5-91 ER 617 226 |
Keywords
- Feedback Control
- Ho:Yag Laser
- Intestine
- Quasi-Constant Temperature Control
- S: Dosimetry
- Temperature Feedback
- Tissue Fusion
- Tissue Welding.
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