Comprehensive genome-scale metabolic model of the human pathogen Cryptococcus neoformans: A platform for understanding pathogen metabolism and identifying new drug targets

Keyphrases

• Metabolism 100%
• Genome-scale Metabolic Model 100%
• Human Pathogens 100%
• New Drug Targets 100%
• Cryptococcus Neoformans 100%
• Growth Rate 25%
• Carbon Source 25%
• Treatment Methods 25%
• Recurring 25%
• Resource Scarcity 25%
• In Silico 25%
• Application Time 25%
• Genome Analysis 25%
• Drug Target 25%
• New Targets 25%
• Amino Acid Metabolism 25%
• Nitrogen Source 25%
• Gene Analysis 25%
• New Treatment Options 25%
• Antifungal Drugs 25%
• Essential Reactions 25%
• Undesirable Side Effects 25%
• Therapeutic Strategies 25%
• Priority Pathogens 25%
• Cryptococcus Species 25%
• Essentiality Analysis 25%
• Cryptococcal Meningitis 25%
• Essential Metabolite 25%
• Source Rate 25%
• Reaction Analysis 25%
• Genome-scale Model 25%
• Neoformans 25%
• Cryptococcus 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Infectious Agent 100%
• Cryptococcus neoformans 100%
• Pathogenesis 100%
• Filobasidiella 66%
• Nitrogen 33%
• Amino Acid 33%
• Side Effect 33%
• Meningoencephalitis 33%
• Infection 33%
• Antifungal Agent 33%
• Disease 33%

Immunology and Microbiology

• Human Pathogen 100%
• Cryptococcus neoformans 100%
• Infectious Agent 100%
• Filobasidiella 66%
• Metabolite 66%
• Amino Acid Metabolism 33%
• Computer Model 33%
• Meningoencephalitis 33%
• Essential Gene 33%