Comparison of photon interaction coefficients for tumor compositions and healthy tissues simulated by Monte Carlo

Ahmet Bozkurt, Aycan Sengul*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

This study compares interaction coefficients of photons (namely, mass attenuation, energy absorption and energy transfer coefficients) for some tumor tissues with simlar healthy tissues. Monte Carlo calculations were performed for adenoidcystic carcinoma, melanoma, rectal adenocarcinoma, sarcoma and squamous cell lung carcinoma. The simulation model involved a monoenergetic point source producing a pencil beam. Depending on the parameter under study, average flux, energy flux, or dose deposition from photons that travels in an absorber were scored in the range of 10 keV-20 MeV energy using MCNP6.1. The same model was used to compute the interaction coefficients of health tissues (namely, gastrointestinal tract-small intestine wall, lungs-parenchyma, salivary glands, skin, soft tissue (female+male)) for comparison purposes. The results showed that, depending on the contents of the tumor samples, photon interaction coefficients of a tumor may differ from those of a similar healthy tissue. This behavior was distinct, especially for energies up to 100 keV, and was attributed to the presence of relatively higher atomic number elements in the absorber.

Original languageEnglish
Article numberP07035
JournalJournal of Instrumentation
Volume19
Issue number7
DOIs
Publication statusPublished - 1 Jul 2024

Bibliographical note

Publisher Copyright:
© 2024 IOP Publishing Ltd and Sissa Medialab.

Keywords

  • Algorithms and Software for radiotherapy
  • Models and simulations
  • Radiation damage monitoring systems
  • Simulation methods and programs

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