Chitosan coated liposome dispersions loaded with cacao hull waste extract: Effect of spray drying on physico-chemical stability and in vitro bioaccessibility

Gokce Altin, Mine Gültekin-Özgüven, Beraat Ozcelik*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

60 Citations (Scopus)

Abstract

Cocoa hull waste phenolic extract (CHWPE)1 were encapsulated by fine-disperse anionic liposomes at optimum concentration of 0.2% (w/v) with encapsulation efficiency of 73.6%. Primary anionic liposomes were coated with cationic chitosan (0.4%, w/v) by layer-by-layer deposition method and obtained secondary liposomes were spray dried using maltodextrin as a carrier agent. Bioaccessibility of CHWPE was increased at least 6 fold when encapsulated in secondary liposomes and it did not change during spray drying process after in-vitro digestion. Changes in major phenolic compounds, namely, catechin, epicatechin, quercetin, ferulic acid, gallic acid, p-coumaric acid, syringic acid, transcinnamic acid, vanilic acid and vanillin were investigated before and after in-vitro digestion. p-coumaric acid was the main phenolic compound detected in secondary liposome dispersion with CHWPE, CHWPE powder, and liposomal powder with CHWPE.

Original languageEnglish
Pages (from-to)91-98
Number of pages8
JournalJournal of Food Engineering
Volume223
DOIs
Publication statusPublished - Apr 2018

Bibliographical note

Publisher Copyright:
© 2017 Elsevier Ltd

Keywords

  • In vitro digestion
  • Phenolics
  • Primary liposomes
  • Secondary liposomes
  • SEM
  • Spray drying

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