Centri-voltammetric dopamine detection

Sinan Cemgil Sultan; Esma Sezer; Yudum Tepeli; Ulku Anik

doi:10.1039/c4ra04887c

Centri-voltammetric dopamine detection

Sinan Cemgil Sultan, Esma Sezer, Yudum Tepeli, Ulku Anik^*

^*Corresponding author for this work

Department of Chemistry

Mugla Sıtkı Kocman University

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Centri-voltammetry, which includes the combination of centrifugal forces and voltammetry, is a kind of new method. In this work, centri-voltammetry was applied for the detection of the very important biological molecule Dopamin (DA) for the first time. After optimization of centrifugal parameters, a linear range was obtained between 5 × 10^-9 M and 5 × 10 ^-6 M DA with the equation y = 7.8206x - 0.3575 and correlation coefficient R² = 0.997. The RSD value was calculated for 10 ^-7 M DA (n = 5) and found to be 1.37%. LOD (3 s m^-1) and LOQ (10 s m^-1) values were also calculated and found to be 1.007 × 10^-9 M and 1.023× × 10^-9 M, respectively. Also the detection of DA in the presence of ascorbic acid (AA) has been conducted and it has been found that in the presence of 100 fold AA, it is possible to obtain accessable DA peaks. This journal is

Original language	English
Pages (from-to)	31489-31492
Number of pages	4
Journal	RSC Advances
Volume	4
Issue number	59
DOIs	https://doi.org/10.1039/c4ra04887c
Publication status	Published - 2014

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T1 - Centri-voltammetric dopamine detection

AU - Cemgil Sultan, Sinan

AU - Sezer, Esma

AU - Tepeli, Yudum

AU - Anik, Ulku

PY - 2014

Y1 - 2014

N2 - Centri-voltammetry, which includes the combination of centrifugal forces and voltammetry, is a kind of new method. In this work, centri-voltammetry was applied for the detection of the very important biological molecule Dopamin (DA) for the first time. After optimization of centrifugal parameters, a linear range was obtained between 5 × 10-9 M and 5 × 10 -6 M DA with the equation y = 7.8206x - 0.3575 and correlation coefficient R2 = 0.997. The RSD value was calculated for 10 -7 M DA (n = 5) and found to be 1.37%. LOD (3 s m-1) and LOQ (10 s m-1) values were also calculated and found to be 1.007 × 10-9 M and 1.023× × 10-9 M, respectively. Also the detection of DA in the presence of ascorbic acid (AA) has been conducted and it has been found that in the presence of 100 fold AA, it is possible to obtain accessable DA peaks. This journal is

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Centri-voltammetric dopamine detection

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