Cefoperazone metal complexes and their antimicrobial investigations

Mehmet Emin Çinar, Taner Erdoğan, Ayşegül Gölcü*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Transition metal (Cd(II), Co(II), Cu(II), Fe(III), Ni(II), Pd(II), Pt(II), Ru(III), Zn(II)) complexes of cefoperazone (CFP) were synthesized and their spectroscopic (IR, UV-Vis), magnetic, thermal (DTA-TG), and mass spectral investigations were conducted to characterize the metal-based complexes. Detailed insights into the electronic structures were provided by performing density functional theory (DFT) computations. Their antimicrobial studies were realized rendering their activities compared to that of the commercial cefoperazone.

Original languageEnglish
Pages (from-to)375-390
Number of pages16
JournalJournal of the Turkish Chemical Society, Section A: Chemistry
Volume8
Issue number2
DOIs
Publication statusPublished - 2021

Bibliographical note

Publisher Copyright:
© 2021, Turkish Chemical Society. All rights reserved.

Keywords

  • Antimicrobial studies
  • Cefoperazone
  • Computation
  • Metal complexes

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