Abstract
Transition metal (Cd(II), Co(II), Cu(II), Fe(III), Ni(II), Pd(II), Pt(II), Ru(III), Zn(II)) complexes of cefoperazone (CFP) were synthesized and their spectroscopic (IR, UV-Vis), magnetic, thermal (DTA-TG), and mass spectral investigations were conducted to characterize the metal-based complexes. Detailed insights into the electronic structures were provided by performing density functional theory (DFT) computations. Their antimicrobial studies were realized rendering their activities compared to that of the commercial cefoperazone.
| Original language | English |
|---|---|
| Pages (from-to) | 375-390 |
| Number of pages | 16 |
| Journal | Journal of the Turkish Chemical Society, Section A: Chemistry |
| Volume | 8 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2021 |
Bibliographical note
Publisher Copyright:© 2021, Turkish Chemical Society. All rights reserved.
Funding
The authors wish to thank TUBITAK (Project No: 105T371) for the financial support; Kahramanmaras Sutcu Imam University, Chemistry Department for laboratory environments; and Kahramanmaras Sutcu Imam University, Biology Department for cell culture studies. We thank the Istanbul Technical University for the laboratory (L105) facilities to redo the experiments. We are indebted to the Kocaeli University for the computer time provided.
| Funders | Funder number |
|---|---|
| Chemistry Department | |
| TUBITAK | 105T371 |
| Kocaeli Üniversitesi | |
| Istanbul Teknik Üniversitesi | L105 |
| Kahramanmaraş Sütçü Imam Üniversitesi |
Keywords
- Antimicrobial studies
- Cefoperazone
- Computation
- Metal complexes