Biocompability properties of ZrO2 ceramics and ZrO 2-TiN composites

M. Arin; H. Yazici; G. Goller

Biocompability properties of ZrO₂ ceramics and ZrO ₂-TiN composites

M. Arin^*, H. Yazici, G. Goller

^*Corresponding author for this work

Department of Metallurgical and Materials Engineering

Istanbul Technical University

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

In order to study bicompability properties of fully dense ZrO₂ ceramics containing 2-3 mol% Y₂O₃ stabilizer, and ZO ₂-TiN composites containing 1-1.75 mol Y₂O₃ and 1 mol% Nd₂O₃ stabilizers, and electrical conductive TiN particles (40-60 vol%), cell viability was evaluated based on the reduction of tetrazolium salt to formazan crystals by living cells, the alkaline phosphatase production was investigated, and nitrite quantification was done for indirect evaluation of osteoblast NO production. The samples were defined biocompatible since there is not any significant change observed in the physiological functions of the cells when incubated together.

Original language	English
Pages (from-to)	51-54
Number of pages	4
Journal	Key Engineering Materials
Volume	396-398
Publication status	Published - 2009

Keywords

Alkaline phosphatase activity
Biocompability
Cellular viability
Nitric oxide measurement
Osteoblasts
TiN
ZrO

Cite this

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title = "Biocompability properties of ZrO2 ceramics and ZrO 2-TiN composites",

abstract = "In order to study bicompability properties of fully dense ZrO2 ceramics containing 2-3 mol% Y2O3 stabilizer, and ZO 2-TiN composites containing 1-1.75 mol Y2O3 and 1 mol% Nd2O3 stabilizers, and electrical conductive TiN particles (40-60 vol%), cell viability was evaluated based on the reduction of tetrazolium salt to formazan crystals by living cells, the alkaline phosphatase production was investigated, and nitrite quantification was done for indirect evaluation of osteoblast NO production. The samples were defined biocompatible since there is not any significant change observed in the physiological functions of the cells when incubated together.",

keywords = "Alkaline phosphatase activity, Biocompability, Cellular viability, Nitric oxide measurement, Osteoblasts, TiN, ZrO",

author = "M. Arin and H. Yazici and G. Goller",

year = "2009",

language = "English",

volume = "396-398",

pages = "51--54",

journal = "Key Engineering Materials",

issn = "1013-9826",

publisher = "Trans Tech Publications",

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TY - JOUR

T1 - Biocompability properties of ZrO2 ceramics and ZrO 2-TiN composites

AU - Arin, M.

AU - Yazici, H.

AU - Goller, G.

PY - 2009

Y1 - 2009

N2 - In order to study bicompability properties of fully dense ZrO2 ceramics containing 2-3 mol% Y2O3 stabilizer, and ZO 2-TiN composites containing 1-1.75 mol Y2O3 and 1 mol% Nd2O3 stabilizers, and electrical conductive TiN particles (40-60 vol%), cell viability was evaluated based on the reduction of tetrazolium salt to formazan crystals by living cells, the alkaline phosphatase production was investigated, and nitrite quantification was done for indirect evaluation of osteoblast NO production. The samples were defined biocompatible since there is not any significant change observed in the physiological functions of the cells when incubated together.

AB - In order to study bicompability properties of fully dense ZrO2 ceramics containing 2-3 mol% Y2O3 stabilizer, and ZO 2-TiN composites containing 1-1.75 mol Y2O3 and 1 mol% Nd2O3 stabilizers, and electrical conductive TiN particles (40-60 vol%), cell viability was evaluated based on the reduction of tetrazolium salt to formazan crystals by living cells, the alkaline phosphatase production was investigated, and nitrite quantification was done for indirect evaluation of osteoblast NO production. The samples were defined biocompatible since there is not any significant change observed in the physiological functions of the cells when incubated together.

KW - Alkaline phosphatase activity

KW - Biocompability

KW - Cellular viability

KW - Nitric oxide measurement

KW - Osteoblasts

KW - TiN

KW - ZrO

UR - http://www.scopus.com/inward/record.url?scp=58849159756&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:58849159756

SN - 1013-9826

VL - 396-398

SP - 51

EP - 54

JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

Biocompability properties of ZrO₂ ceramics and ZrO ₂-TiN composites

Abstract

Keywords

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