Bioactivity and antimicrobial properties of PMMA/Ag2O acrylic bone cement collagen coated

S. Cavalu*, V. Simon, G. Goller, I. Akin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

PMMA/Ag2O bone cements with collagen coating were prepared in order to improve their biomineralisation, biocompatibitity and antibacterial properties as well. ATR FTIR spectroscopy analysis demonstrated that collagen electrodeposition on their surface depends on the silver content in samples. In vitro tests, performed in simulated body fluid (SBF) during three weeks of SBF incubation, revealed the dissolution profile of Ag+ from the acrylic matrix, the results being in concordance with antibacterial tests performed against Escherichia coli and Staphylococcus aureus. The mineralization process upon incubation was confirmed by the surface morphology analyses (SEM) combined with ATR FTIR, which evidenced the phosphate characteristic bands of hydroxyapatite, depending on the silver oxide content in the samples.

Original languageEnglish
Pages (from-to)779-790
Number of pages12
JournalDigest Journal of Nanomaterials and Biostructures
Volume6
Issue number2
Publication statusPublished - 2011

Keywords

  • Acrylic bone cement
  • Antimicrobial activity
  • ATR FTIR
  • Collagen
  • Sem

Fingerprint

Dive into the research topics of 'Bioactivity and antimicrobial properties of PMMA/Ag2O acrylic bone cement collagen coated'. Together they form a unique fingerprint.

Cite this