Bioactive components and anti-diabetic properties of Moringa oleifera Lam

Fang Wang; Yifan Bao; Chen Zhang; Libin Zhan; Washim Khan; Sahifa Siddiqua; Sayeed Ahmad; Esra Capanoglu; Krystyna Skalicka-Woźniak; Liang Zou; Jesus Simal-Gandara; Hui Cao; Zebin Weng; Xinchun Shen; Jianbo Xiao

doi:10.1080/10408398.2020.1870099

Bioactive components and anti-diabetic properties of Moringa oleifera Lam

Fang Wang
, Yifan Bao
, Chen Zhang
, Libin Zhan
, Washim Khan
, Sahifa Siddiqua
, Sayeed Ahmad
, Esra Capanoglu
, Krystyna Skalicka-Woźniak
, Liang Zou
, Jesus Simal-Gandara
, Hui Cao
, Zebin Weng^*
, Xinchun Shen^*
, Jianbo Xiao^*

^*Corresponding author for this work

Department of Food Engineering

College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing
Nanjing University of Finance & Economics
School of Traditional Chinese Medicine
Nanjing University of Chinese Medicine
School of Pharmaceutical Education and Research
Bioactive Natural Product Laboratory
Independent Laboratory of Natural Products Chemistry
Medical University of Lublin
Chengdu University
Nutrition and Bromatology Group
University of Vigo
College of Food Science and Technology
Guangdong Ocean University
International Research Center for Food Nutrition and Safety
Jiangsu University

Research output: Contribution to journal › Review article › peer-review

57 Citations (Scopus)

Abstract

Moringa oleifera Lam. is a perennial tropical deciduous tree with high economic and pharmaceutical value. As an edible plant, M. oleifera Lam. is rich in nutrients, such as proteins, amino acids, mineral elements and vitamins. Besides, it also contains an important number of bioactive phytochemicals, such as polysaccharides, flavonoids, alkaloids, glucosinolates and isothiocyanates. M. oleifera for long has been used as a natural anti-diabetic herb in India and other Asian countries. Thus, the anti-diabetic properties of Moringa plant have evolved highly attention to the researchers. In the last twenty years, a huge number of new chemical structures and their pharmacological activities have been reported in particularly the anti-diabetic properties. The current review highlighted the bioactive phytochemicals from M. Oleifera. Moreover, evidence regarding the therapeutic potential of M. oleifera for diabetes including experimental and clinical data was presented and the underlying mechanisms were revealed in order to provide insights for the development of novel drugs.

Original language	English
Pages (from-to)	3873-3897
Number of pages	25
Journal	Critical Reviews in Food Science and Nutrition
Volume	62
Issue number	14
DOIs	https://doi.org/10.1080/10408398.2020.1870099
Publication status	Published - 2022

Bibliographical note

Publisher Copyright:
© 2020 Taylor & Francis Group, LLC.

Funding

This work was financially supported by the National Natural Science Foundation of China (31800280, 81903940), the Natural Science Foundation of Jiangsu Province of China (BK20180817, BK20190804), the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (18KJB550006). It was also supported in part by the National Key R&D Program of China (2016YFD0400200) and the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).

Funders	Funder number
National Natural Science Foundation of China	81903940, 31800280
Natural Science Foundation of Jiangsu Province	BK20190804, BK20180817
Natural Science Research of Jiangsu Higher Education Institutions of China	18KJB550006
National Key Research and Development Program of China	2016YFD0400200
Priority Academic Program Development of Jiangsu Higher Education Institutions

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Bioactive phytochemicals
Moringa oleiferaLam
clinical application
diabetes
nutrition

Access to Document

10.1080/10408398.2020.1870099

Cite this

Wang, F., Bao, Y., Zhang, C., Zhan, L., Khan, W., Siddiqua, S., Ahmad, S., Capanoglu, E., Skalicka-Woźniak, K., Zou, L., Simal-Gandara, J., Cao, H., Weng, Z., Shen, X., & Xiao, J. (2022). Bioactive components and anti-diabetic properties of Moringa oleifera Lam. Critical Reviews in Food Science and Nutrition, 62(14), 3873-3897. https://doi.org/10.1080/10408398.2020.1870099

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title = "Bioactive components and anti-diabetic properties of Moringa oleifera Lam",

abstract = "Moringa oleifera Lam. is a perennial tropical deciduous tree with high economic and pharmaceutical value. As an edible plant, M. oleifera Lam. is rich in nutrients, such as proteins, amino acids, mineral elements and vitamins. Besides, it also contains an important number of bioactive phytochemicals, such as polysaccharides, flavonoids, alkaloids, glucosinolates and isothiocyanates. M. oleifera for long has been used as a natural anti-diabetic herb in India and other Asian countries. Thus, the anti-diabetic properties of Moringa plant have evolved highly attention to the researchers. In the last twenty years, a huge number of new chemical structures and their pharmacological activities have been reported in particularly the anti-diabetic properties. The current review highlighted the bioactive phytochemicals from M. Oleifera. Moreover, evidence regarding the therapeutic potential of M. oleifera for diabetes including experimental and clinical data was presented and the underlying mechanisms were revealed in order to provide insights for the development of novel drugs.",

keywords = "Bioactive phytochemicals, Moringa oleiferaLam, clinical application, diabetes, nutrition",

author = "Fang Wang and Yifan Bao and Chen Zhang and Libin Zhan and Washim Khan and Sahifa Siddiqua and Sayeed Ahmad and Esra Capanoglu and Krystyna Skalicka-Wo{\'z}niak and Liang Zou and Jesus Simal-Gandara and Hui Cao and Zebin Weng and Xinchun Shen and Jianbo Xiao",

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year = "2022",

doi = "10.1080/10408398.2020.1870099",

language = "English",

volume = "62",

pages = "3873--3897",

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Wang, F, Bao, Y, Zhang, C, Zhan, L, Khan, W, Siddiqua, S, Ahmad, S, Capanoglu, E, Skalicka-Woźniak, K, Zou, L, Simal-Gandara, J, Cao, H, Weng, Z, Shen, X & Xiao, J 2022, 'Bioactive components and anti-diabetic properties of Moringa oleifera Lam', Critical Reviews in Food Science and Nutrition, vol. 62, no. 14, pp. 3873-3897. https://doi.org/10.1080/10408398.2020.1870099

TY - JOUR

T1 - Bioactive components and anti-diabetic properties of Moringa oleifera Lam

AU - Wang, Fang

AU - Bao, Yifan

AU - Zhang, Chen

AU - Zhan, Libin

AU - Khan, Washim

AU - Siddiqua, Sahifa

AU - Ahmad, Sayeed

AU - Capanoglu, Esra

AU - Skalicka-Woźniak, Krystyna

AU - Zou, Liang

AU - Simal-Gandara, Jesus

AU - Cao, Hui

AU - Weng, Zebin

AU - Shen, Xinchun

AU - Xiao, Jianbo

PY - 2022

Y1 - 2022

N2 - Moringa oleifera Lam. is a perennial tropical deciduous tree with high economic and pharmaceutical value. As an edible plant, M. oleifera Lam. is rich in nutrients, such as proteins, amino acids, mineral elements and vitamins. Besides, it also contains an important number of bioactive phytochemicals, such as polysaccharides, flavonoids, alkaloids, glucosinolates and isothiocyanates. M. oleifera for long has been used as a natural anti-diabetic herb in India and other Asian countries. Thus, the anti-diabetic properties of Moringa plant have evolved highly attention to the researchers. In the last twenty years, a huge number of new chemical structures and their pharmacological activities have been reported in particularly the anti-diabetic properties. The current review highlighted the bioactive phytochemicals from M. Oleifera. Moreover, evidence regarding the therapeutic potential of M. oleifera for diabetes including experimental and clinical data was presented and the underlying mechanisms were revealed in order to provide insights for the development of novel drugs.

AB - Moringa oleifera Lam. is a perennial tropical deciduous tree with high economic and pharmaceutical value. As an edible plant, M. oleifera Lam. is rich in nutrients, such as proteins, amino acids, mineral elements and vitamins. Besides, it also contains an important number of bioactive phytochemicals, such as polysaccharides, flavonoids, alkaloids, glucosinolates and isothiocyanates. M. oleifera for long has been used as a natural anti-diabetic herb in India and other Asian countries. Thus, the anti-diabetic properties of Moringa plant have evolved highly attention to the researchers. In the last twenty years, a huge number of new chemical structures and their pharmacological activities have been reported in particularly the anti-diabetic properties. The current review highlighted the bioactive phytochemicals from M. Oleifera. Moreover, evidence regarding the therapeutic potential of M. oleifera for diabetes including experimental and clinical data was presented and the underlying mechanisms were revealed in order to provide insights for the development of novel drugs.

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EP - 3897

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IS - 14

ER -

Bioactive components and anti-diabetic properties of Moringa oleifera Lam

Abstract

Bibliographical note

Funding

UN SDGs

Keywords

Access to Document

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