Bioactive components and anti-diabetic properties of Moringa oleifera Lam

Fang Wang, Yifan Bao, Chen Zhang, Libin Zhan, Washim Khan, Sahifa Siddiqua, Sayeed Ahmad, Esra Capanoglu, Krystyna Skalicka-Woźniak, Liang Zou, Jesus Simal-Gandara, Hui Cao, Zebin Weng*, Xinchun Shen*, Jianbo Xiao*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

24 Citations (Scopus)

Abstract

Moringa oleifera Lam. is a perennial tropical deciduous tree with high economic and pharmaceutical value. As an edible plant, M. oleifera Lam. is rich in nutrients, such as proteins, amino acids, mineral elements and vitamins. Besides, it also contains an important number of bioactive phytochemicals, such as polysaccharides, flavonoids, alkaloids, glucosinolates and isothiocyanates. M. oleifera for long has been used as a natural anti-diabetic herb in India and other Asian countries. Thus, the anti-diabetic properties of Moringa plant have evolved highly attention to the researchers. In the last twenty years, a huge number of new chemical structures and their pharmacological activities have been reported in particularly the anti-diabetic properties. The current review highlighted the bioactive phytochemicals from M. Oleifera. Moreover, evidence regarding the therapeutic potential of M. oleifera for diabetes including experimental and clinical data was presented and the underlying mechanisms were revealed in order to provide insights for the development of novel drugs.

Original languageEnglish
Pages (from-to)3873-3897
Number of pages25
JournalCritical Reviews in Food Science and Nutrition
Volume62
Issue number14
DOIs
Publication statusPublished - 2022

Bibliographical note

Publisher Copyright:
© 2020 Taylor & Francis Group, LLC.

Funding

This work was financially supported by the National Natural Science Foundation of China (31800280, 81903940), the Natural Science Foundation of Jiangsu Province of China (BK20180817, BK20190804), the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (18KJB550006). It was also supported in part by the National Key R&D Program of China (2016YFD0400200) and the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).

FundersFunder number
National Natural Science Foundation of China81903940, 31800280
Natural Science Foundation of Jiangsu ProvinceBK20190804, BK20180817
Natural Science Research of Jiangsu Higher Education Institutions of China18KJB550006
National Key Research and Development Program of China2016YFD0400200
Priority Academic Program Development of Jiangsu Higher Education Institutions

    Keywords

    • Bioactive phytochemicals
    • clinical application
    • diabetes
    • Moringa oleiferaLam
    • nutrition

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