Apium plants: Beyond simple food and phytopharmacological applications

Bahare Salehi; Alessandro Venditti; Claudio Frezza; Aysun Yücetepe; Ümit Altuntaş; Sibel Uluata; Monica Butnariu; Ioan Sarac; Shabnum Shaheen; Spyridon A. Petropoulos; Karl R. Matthews; Ceyda Sibel Kiliç; Maria Atanassova; Charles Oluwaseun Adetunji; Adedayo Oluwaseun Ademiluyi; Beraat Özçelik; Patrick Valere Tsouh Fokou; Natália Martins; William C. Cho; Javad Sharifi-Rad

doi:10.3390/app9173547

Apium plants: Beyond simple food and phytopharmacological applications

Bahare Salehi, Alessandro Venditti, Claudio Frezza, Aysun Yücetepe, Ümit Altuntaş, Sibel Uluata, Monica Butnariu, Ioan Sarac, Shabnum Shaheen, Spyridon A. Petropoulos, Karl R. Matthews, Ceyda Sibel Kiliç, Maria Atanassova, Charles Oluwaseun Adetunji, Adedayo Oluwaseun Ademiluyi, Beraat Özçelik^*, Patrick Valere Tsouh Fokou, Natália Martins, William C. Cho, Javad Sharifi-Rad

^*Corresponding author for this work

Department of Food Engineering

Research output: Contribution to journal › Review article › peer-review

31 Citations (Scopus)

Abstract

Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.

Original language	English
Article number	3547
Journal	Applied Sciences (Switzerland)
Volume	9
Issue number	17
DOIs	https://doi.org/10.3390/app9173547
Publication status	Published - 1 Sept 2019

Bibliographical note

Publisher Copyright:
© 2019 by the authors.

Funding

N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT-Portugal) for the strategic project ref. UID/BIM/04293/2013 and "NORTE2020-Northern Regional Operational Program" (NORTE-01-0145-FEDER-000012).This research received no external funding. Acknowledgments: N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT-Portugal) for the strategic project ref. UID/BIM/04293/2013 and “NORTE2020-Northern Regional Operational Program” (NORTE-01-0145-FEDER-000012).

Funders	Funder number
FCT-Portugal
Fundação para a Ciência e a Tecnologia	UID/BIM/04293/2013, NORTE-01-0145-FEDER-000012

Keywords

Apium
Botany
Medicinal use
Pharmacological properties
Phytochemicals

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/app9173547

Cite this

Salehi, B., Venditti, A., Frezza, C., Yücetepe, A., Altuntaş, Ü., Uluata, S., Butnariu, M., Sarac, I., Shaheen, S., Petropoulos, S. A., Matthews, K. R., Kiliç, C. S., Atanassova, M., Adetunji, C. O., Ademiluyi, A. O., Özçelik, B., Fokou, P. V. T., Martins, N., Cho, W. C., & Sharifi-Rad, J. (2019). Apium plants: Beyond simple food and phytopharmacological applications. Applied Sciences (Switzerland), 9(17), Article 3547. https://doi.org/10.3390/app9173547

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title = "Apium plants: Beyond simple food and phytopharmacological applications",

abstract = "Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.",

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note = "Publisher Copyright: {\textcopyright} 2019 by the authors.",

year = "2019",

month = sep,

day = "1",

doi = "10.3390/app9173547",

language = "English",

volume = "9",

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Salehi, B, Venditti, A, Frezza, C, Yücetepe, A, Altuntaş, Ü, Uluata, S, Butnariu, M, Sarac, I, Shaheen, S, Petropoulos, SA, Matthews, KR, Kiliç, CS, Atanassova, M, Adetunji, CO, Ademiluyi, AO, Özçelik, B, Fokou, PVT, Martins, N, Cho, WC & Sharifi-Rad, J 2019, 'Apium plants: Beyond simple food and phytopharmacological applications', Applied Sciences (Switzerland), vol. 9, no. 17, 3547. https://doi.org/10.3390/app9173547

TY - JOUR

T1 - Apium plants

T2 - Beyond simple food and phytopharmacological applications

AU - Salehi, Bahare

AU - Venditti, Alessandro

AU - Frezza, Claudio

AU - Yücetepe, Aysun

AU - Altuntaş, Ümit

AU - Uluata, Sibel

AU - Butnariu, Monica

AU - Sarac, Ioan

AU - Shaheen, Shabnum

AU - Petropoulos, Spyridon A.

AU - Matthews, Karl R.

AU - Kiliç, Ceyda Sibel

AU - Atanassova, Maria

AU - Adetunji, Charles Oluwaseun

AU - Ademiluyi, Adedayo Oluwaseun

AU - Özçelik, Beraat

AU - Fokou, Patrick Valere Tsouh

AU - Martins, Natália

AU - Cho, William C.

AU - Sharifi-Rad, Javad

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.

AB - Apium plants belong to the Apiaceae family and are included among plants that have been in use in traditional medicine for thousands of years worldwide, including in the Mediterranean, as well as the tropical and subtropical regions of Asia and Africa. Some highlighted medical benefits include prevention of coronary and vascular diseases. Their phytochemical constituents consist of bergapten, flavonoids, glycosides, furanocoumarins, furocoumarin, limonene, psoralen, xanthotoxin, and selinene. Some of their pharmacological properties include anticancer, antioxidant, antimicrobial, antifungal, nematocidal, anti-rheumatism, antiasthma, anti-bronchitis, hepatoprotective, appetizer, anticonvulsant, antispasmodic, breast milk inducer, anti-jaundice, antihypertensive, anti-dysmenorrhea, prevention of cardiovascular diseases, and spermatogenesis induction. The present review summarizes data on ecology, botany, cultivation, habitat, medicinal use, phytochemical composition, preclinical and clinical pharmacological efficacy of Apium plants and provides future direction on how to take full advantage of Apium plants for the optimal benefit to mankind.

KW - Apium

KW - Botany

KW - Medicinal use

KW - Pharmacological properties

KW - Phytochemicals

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U2 - 10.3390/app9173547

DO - 10.3390/app9173547

M3 - Review article

AN - SCOPUS:85072296771

SN - 2076-3417

VL - 9

JO - Applied Sciences (Switzerland)

JF - Applied Sciences (Switzerland)

IS - 17

M1 - 3547

ER -

Apium plants: Beyond simple food and phytopharmacological applications

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

Access to Document

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