Antibacterial nano cerium oxide/chitosan/cellulose acetate composite films as potential wound dressing

Zeynep Kalaycıoğlu, Nilay Kahya, Veselina Adımcılar, Hakan Kaygusuz, Emrah Torlak, Gülşen Akın-Evingür, F. Bedia Erim*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

90 Citations (Scopus)

Abstract

Novel chitosan and cellulose acetate polymer composites with nanosized cerium oxide were prepared as potential wound dressing materials. Chitosan and cellulose acetate are natural polymer derivatives with biocompatible properties. Both polymers can be dissolved in formic acid. The polymer composite was formed by solvent-casting method. The formed films were not soluble in water. In order to improve antibacterial, thermal, and mechanical properties of the composite material, films were loaded with nanosized cerium oxide. Films were characterized with thermogravimetric, scanning electron microscopy with energy-dispersive X-ray spectroscopy, mechanical, ultraviolet-visible light transmittance, water solubility, pH, moisture content, water vapor transmission rate, swelling, and antibacterial tests. The physical properties and antibacterial characteristics of the films are promising for further research as a potential wound covering material.

Original languageEnglish
Article number109777
JournalEuropean Polymer Journal
Volume133
DOIs
Publication statusPublished - 15 Jun 2020

Bibliographical note

Publisher Copyright:
© 2020 Elsevier Ltd

Keywords

  • Antibacterial film
  • Characterization
  • Nano Ceria
  • Wound dressing

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