Analysis of the effects of different pulsatile inlet profiles on the hemodynamical properties of blood flow in patient specific carotid artery with stenosis

Senol Piskin*, M. Serdar Celebi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)

Abstract

In this study the biomechanical characteristics of a realistic carotid artery [3] are studied numerically using different inlet velocity profiles. Several experimental data measured [32] at the common carotid artery are used as inlet boundary conditions. Computation domain is generated using computed tomography (CT) data of a real patient. Three dimensional (3D) transient NS equations are solved, in this actual domain, using the proposed boundary conditions. Effects of different input conditions on the results of simulation are discussed. Main parameters such as velocity profiles, wall shear stress (WSS) and pressure distributions are investigated at the critical parts of the carotid artery such as bifurcation and sinusoidal enlargement regions. Results show that the input boundary conditions and slope/curvature discontinuities in the realistic geometry have strong relationship with the velocity, pressure and WSS distributions as expected. The most important conclusion obtained from our model is the existence of negative relation between velocity at several inner points of the internal carotid artery and velocity at the inlet of the common carotid artery.

Original languageEnglish
Pages (from-to)717-728
Number of pages12
JournalComputers in Biology and Medicine
Volume43
Issue number6
DOIs
Publication statusPublished - 1 Jul 2013

Keywords

  • Biomechanics
  • Blood flow
  • Carotid artery bifurcation
  • CFD
  • Computational fluid dynamics
  • Computed tomography
  • CT
  • Real patient data
  • Simulation
  • Wall shear stress
  • Womersley velocity profile
  • WSS

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