TY - JOUR
T1 - A Review of Recent Studies on the Antioxidant and Anti-Infectious Properties of Senna Plants
AU - Alshehri, Mohammed M.
AU - Quispe, Cristina
AU - Herrera-Bravo, Jesús
AU - Sharifi-Rad, Javad
AU - Tutuncu, Sena
AU - Aydar, Elif Feyza
AU - Topkaya, Cansu
AU - Mertdinc, Zehra
AU - Ozcelik, Beraat
AU - Aital, Mahima
AU - Kumar, N. V.Anil
AU - Lapava, Natallia
AU - Rajkovic, Jovana
AU - Ertani, Andrea
AU - Nicola, Silvana
AU - Semwal, Prabhakar
AU - Painuli, Sakshi
AU - González-Contreras, Carlos
AU - Martorell, Miquel
AU - Butnariu, Monica
AU - Bagiu, Iulia Cristina
AU - Bagiu, Radu Vasile
AU - Barbhai, Mrunal D.
AU - Kumar, Manoj
AU - Daştan, Sevgi Durna
AU - Calina, Daniela
AU - Cho, William C.
N1 - Publisher Copyright:
© 2022 Mohammed M. Alshehri et al.
PY - 2022
Y1 - 2022
N2 - The use of phytochemicals is gaining interest for the treatment of metabolic syndromes over the synthetic formulation of drugs. Senna is evolving as one of the important plants which have been vastly studied for its beneficial effects. Various parts of Senna species including the root, stem, leaves, and flower are found rich in numerous phytochemicals. In vitro, in vivo, and clinical experiments established that extracts from Senna plants have diverse beneficial effects by acting as a strong antioxidant and antimicrobial agent. In this review, Senna genus is comprehensively discussed in terms of its botanical characteristics, traditional use, geographic presence, and phytochemical profile. The bioactive compound richness contributes to the biological activity of Senna plant extracts. The review emphasizes on the in vivo and in vitro antioxidant and anti-infectious properties of the Senna plant. Preclinical studies confirmed the beneficial effects of the Senna plant extracts and its bioactive components in regard to the health-promoting activities. The safety, side effects, and therapeutic limitations of the Senna plant are also discussed in this review. Additional research is necessary to utilize the phenolic compounds towards its use as an alternative to pharmacological treatments and even as an ingredient in functional foods.
AB - The use of phytochemicals is gaining interest for the treatment of metabolic syndromes over the synthetic formulation of drugs. Senna is evolving as one of the important plants which have been vastly studied for its beneficial effects. Various parts of Senna species including the root, stem, leaves, and flower are found rich in numerous phytochemicals. In vitro, in vivo, and clinical experiments established that extracts from Senna plants have diverse beneficial effects by acting as a strong antioxidant and antimicrobial agent. In this review, Senna genus is comprehensively discussed in terms of its botanical characteristics, traditional use, geographic presence, and phytochemical profile. The bioactive compound richness contributes to the biological activity of Senna plant extracts. The review emphasizes on the in vivo and in vitro antioxidant and anti-infectious properties of the Senna plant. Preclinical studies confirmed the beneficial effects of the Senna plant extracts and its bioactive components in regard to the health-promoting activities. The safety, side effects, and therapeutic limitations of the Senna plant are also discussed in this review. Additional research is necessary to utilize the phenolic compounds towards its use as an alternative to pharmacological treatments and even as an ingredient in functional foods.
UR - https://www.scopus.com/pages/publications/85124599260
U2 - 10.1155/2022/6025900
DO - 10.1155/2022/6025900
M3 - Review article
C2 - 35154569
AN - SCOPUS:85124599260
SN - 1942-0900
VL - 2022
JO - Oxidative Medicine and Cellular Longevity
JF - Oxidative Medicine and Cellular Longevity
M1 - 6025900
ER -